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AM65

Sigma-Aldrich

Anti-Caspase-3 (Ab-4) Mouse mAb (AM1.31-11)

liquid, clone AM1.31-11, Calbiochem®

Synonym(s):

Anti-Apopain, Anti-CASP3, Anti-CPP32, Anti-ICE-3, Anti-LICE, Anti-YAMA

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About This Item

UNSPSC Code:
12352203

biological source

mouse

Quality Level

100

antibody product type

primary antibodies

clone

AM1.31-11, monoclonal

form

liquid

does not contain

preservative

species reactivity

human, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG2a

shipped in

wet ice

storage temp.

−20°C

General description

Anti-Caspase-3 (Ab-4), mouse monoclonal, clone AM1.31-11, recognizes the ~11 kDa active subunit of caspase-3. It is validated for Western blotting and for use with paraffin sections.
Purified mouse monoclonal antibody generated by immunizing mice with the specified immunogen and fusing splenocytes with Sp2/0 mouse myeloma cells. Recognizes the ~11 kDa active subunit of caspase-3.
Recognizes the ~11 kDa active subunit of caspase-3.

Immunogen

recombinant human caspase-3

Application



Immunoblotting (1 g/ml)
Paraffin Sections (2.5 g/ml, heat pre-treatment required)
Frozen Sections (not recommended)
Immunoprecipitation (not recommended)

Packaging

Please refer to vial label for lot-specific concentration.

Analysis Note

Negative Control
trpE (Ab-1)
Positive Control
Recombinant caspase-3 (Cat. No. 235417) or breast carcinoma tissue

Other Notes

Alnemri, E.S. 1997. J. Cell. Biochem.64, 33.
Bayaert, R., et al. 1997. J. Biol. Chem.272, 11694.
Erhardt, P., et al. 1997. J. Biol. Chem.272, 15049.
Inayat-Hussain, S.H., et al. 1997 Hepatology25, 1516.
Krjewska, M., et al. 1997. Cancer Res.57, 1605.
Mashima, T., et al. 1997. Oncogene14, 1007.
McConnell, K.R., et al. 1997. J. Immunol.158, 2083.
Posmantur, R., et al. 1997. J. Neurochem.68, 2328.
Suzuki, A., et al. 1997. Exp. Cell. Res.233, 48.
Liu, X., et al. 1996. J. Biol. Chem.271, 13371.
Quan, L.T., et al. 1996. Proc. Natl. Acad. Sci. USA93, 1972.
Teraoka, H., et al. 1996. FEBS Lett.393, 1.
Tiso, N., et al. 1996. Biochem. Biophys. Res. Commun.225, 983.
Xue, D., et al. 1996. Genes Dev.10, 1073.
Tewari, M., et al. 1995. Cell81, 801.
Fernandes-Alnemri, T., et al. 1994. J. Biol. Chem.269, 30761.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class Code

10-13 - German Storage Class 10 to 13

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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