70050
ミリセチン
≥96.0% (HPLC)
別名:
3,3′,4′,5,5′,7-ヘキサヒドロキシフラボン, カンナビスセチン, ミリセチン
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この商品について
実験式（ヒル表記法）:
C15H10O8
CAS番号:
分子量:
318.24
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
208-463-2
Beilstein/REAXYS Number:
332331
MDL number:
Quality Segment
assay
≥96.0% (HPLC)
form
powder
mp
≥300 °C, >300 °C (lit.)
solubility
ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3
InChI
1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
InChI key
IKMDFBPHZNJCSN-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)
General description
Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.
Application
Myricetin has been used:
- to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats
- as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)
- to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans
- as a reference standard for the quantification of phenolic compounds from Juniperus species
Biochem/physiol Actions
Myricetin exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways. It also displays anti-diabetic and hepatoprotective effects. Myricetin strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy. Myricetin also has various nutraceuticals values and therapeutic effects.
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保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)