A2230
Apyrase from potatoes
High Activity, ATPase ≥600 units/mg protein, lyophilized powder
Synonym(s):
Adenosine 5′-diphosphatase, Adenosine 5′-triphosphatase
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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Product Name
Apyrase from potatoes, High Activity, ATPase ≥600 units/mg protein, lyophilized powder
biological source
potato
form
lyophilized powder
quality
High Activity
ATPase activity
≥600 units/mg protein
secondary activity
≥50 % of base activity ADPase
composition
protein, ≥30%
foreign activity
Acid Phosphatase ≤2% of base activity
shipped in
wet ice
storage temp.
−20°C
Quality Level
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Application
Apyrase is used to hydrolyze nucleoside triphosphates and diphosphates. Apyrase, from Sigma, has been used in inhibition studies of platelet-aggregation . Product A2230 is a high activity apyrase.
At least two isoenzymes are found in different varieties of S. tuberosum: one with a high ATPase/ADPase ratio (∼10) and another with a low ratio (∼1).
Reaction: ATP → ADP+Pi → AMP+2Pi.
Reaction: ATP → ADP+Pi → AMP+2Pi.
Biochem/physiol Actions
Apyrase is found in all eukaryotes and some prokaryotes. Apyrase, from potato, has a crucial role in regulating growth and development. Apyrase is involved in the inactivation of synaptic ATP as a neurotransmitter following nerve stimulation and in the inhibition of ADP induced platelet aggregation to prevent thrombosis . Divalent metal ions are required for activity and best activity is observed with calcium ion at 5 mM.
Other Notes
One unit will liberate 1.0 μmole of inorganic phosphate from ATP or ADP per min at pH 6.5 at 30 °C.
Packaging
Sold on the basis of ATPase units.
Physical form
Lyophilized powder containing potassium succinate buffer salts.
Preparation Note
Derived from red potato
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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