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Home>Events>2019 Purification User Group Meeting
November 12–14, 2019 in Burlington, MA

2019 Purification User Group Meeting

November 12–14, 2019 in Burlington, MA
at our Merck Life Science Center

Vibrant M Merck

Join us for our 14th Annual Purification User Group Meeting taking place at the Merck Life Science Center in Burlington, Massachusetts on November 12–14, 2019. Meet with your industry peers to share best practices, exchange common industry observations, identify existing challenges, and discuss future trends and opportunities in downstream purification processes.


This year's Technical User Forum will be chaired by Kevin Brower Head of Purification Development at Sanofi™, and will cover a variety of topics, including:

Industry trends

  • Next Generation Bioprocessing: An evolution from unit optimization towards intensified, connected or fully continuous downstream processes
  • Operational efficiency through process intensification and its regulatory considerations
  • Challenges and roadblocks to the adoption and implementation of new technologies

Process development and optimization

  • High throughput screening: resin selection, optimization case studies, challenges and needs
  • Tangential Flow Filtration (TFF) intensification and connected processing approaches
  • Impacts of flocculation on downstream with a special focus on chromatography (e.g., lifetime, purification efficiency, etc.)
  • Viral clearance studies on connected downstream processes
  • How to ensure robust impurity removal throughout the downstream processes

Characterization of purification processes

  • Process characterization including the use of DoE tools
  • mAb charge variant and glyco-variant separation
  • Scale-up and scale-down of downstream manufacturing processes
  • Process productivity and cost analysis case studies
  • Process monitoring and control of critical process parameters

The meeting will include presentations, discussions and round tables. If you have a topic you’d like to share, please submit it here:


Submission Deadline: September 15, 2019