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434631 Anti-Lewis x Mouse mAb (P12)

This Anti-Lewis x Mouse mAb (P12) is validated for use in Paraffin Sections for the detection of Lewis x.

Anti-Lewis x Mouse mAb (P12) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Lex

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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      HMMonoclonal Antibody
      Description
      Overview

      This product has been discontinued.



      Recognizes the Lewis x carbohydrate chain in normal kidney.
      Catalogue Number434631
      Brand Family Calbiochem®
      SynonymsAnti-Lex
      References
      ReferencesRee, H.J., et al. 1991. Cancer 67, 1338.
      Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
      Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
      Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.
      Product Information
      FormLiquid
      FormulationTissue Culture Supernatant
      Positive controlNormal kidney tissue
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Paraffin Sections
      Application NotesParaffin Sections (1:10-1:120)
      Application CommentsFor paraffin sections, the recommended working dilution is ≥1:40 (with biotin based detection systems). For fixation, 10% formalin buffered to neutral pH is recommended. Variables associated with assay conditions will dictate the proper working dilutions.
      Biological Information
      Immunogenfresh (non-cultured) human placenta cells
      ImmunogenHuman
      CloneP12
      HostMouse
      IsotypeIgM
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      434631 0

      Documentation

      Anti-Lewis x Mouse mAb (P12) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Lewis x Mouse mAb (P12) Certificates of Analysis

      TitleLot Number
      434631

      References

      Reference overview
      Ree, H.J., et al. 1991. Cancer 67, 1338.
      Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
      Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
      Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-June-2017 JSW
      SynonymsAnti-Lex
      ApplicationParaffin Sections (1:10-1:120)
      DescriptionPurified mouse monoclonal antibody. Recognizes the Lewis x type 2 oligosaccharide chain.
      BackgroundBlood group antigens are a group of molecules formed by sequential addition of saccharides to carbohydrate side chains of lipids and proteins and are detected on erythrocytes, certain epithelial cells and in secretions of some individuals. A, B and H antigens are synthesized by erythrocytes and integrated into their cell membranes. Lewis antigens are not synthesized by erythrocytes but can be absorbed from the plasma onto the surface of red blood cells. Subtle differences in the composition and arrangement of the sugars in the chains are sufficient to generate these distinct specificities. Lewis x is detected in most metastases and invasive cancer cells.
      HostMouse
      Immunogen speciesHuman
      Immunogenfresh (non-cultured) human placenta cells
      CloneP12
      IsotypeIgM
      Specieshuman
      Positive controlNormal kidney tissue
      FormLiquid
      FormulationTissue Culture Supernatant
      Preservative≤0.1% sodium azide
      CommentsFor paraffin sections, the recommended working dilution is ≥1:40 (with biotin based detection systems). For fixation, 10% formalin buffered to neutral pH is recommended. Variables associated with assay conditions will dictate the proper working dilutions.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesRee, H.J., et al. 1991. Cancer 67, 1338.
      Cordon-Cardo, C., et al. 1986. Int. J. Cancer 37, 667.
      Sakamoto, J., et al. 1986. Cancer Res. 46, 1553
      Sakamoto, J., et al. 1984. Mol. Immunol. 21, 1093.

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies