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197225 Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH

Primary Target: A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
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197225
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₅₀H₂₃₄N₄₄O₄₂S

Pricing & Availability

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197225-1MG
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      Description
      OverviewA cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.
      Catalogue Number197225
      Brand Family Calbiochem®
      Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
      References
      ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.
      Product Information
      ATP CompetitiveN
      FormOff-white solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₅₀H₂₃₄N₄₄O₄₂S
      Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      197225-1MG 04055977206029

      Documentation

      Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem Certificates of Analysis

      TitleLot Number
      197225

      References

      Reference overview
      Wang, J-L., et al. 2000. Cancer Res. 60, 1498.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2008 RFH
      Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
      DescriptionA cell-permeable, mutated cpm-1285 peptide analog where Leu151 is replaced by Ala. Does not induce apoptosis and displays about 15 fold lower Bcl-2 binding. Suitable for use as a negative control.
      FormOff-white solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
      Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
      Toxicity Standard Handling
      ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.