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371820 G-Protein βγ Binding Peptide, mSIRK(L9A) - Calbiochem

A cell-permeable, single point mutated (Leu⁹ to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: mSIRK(L9A), myr-SIRKALNIAGYPDYD-OH

Primary Target: G-protein βγ
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371820
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₀H₁₄₄N₂₀O₂₅

Pricing & Availability

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371820-1MG
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      		 Glass bottle 1 mg
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      Description
      OverviewA cell-permeable, single point mutated (Leu9 to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK). Does not enhance ERK1/2 phosphorylation and serves as a negative control for studies involving mSIRK (Cat. No. 371818).
      Catalogue Number371820
      Brand Family Calbiochem®
      SynonymsmSIRK(L9A), myr-SIRKALNIAGYPDYD-OH
      References
      ReferencesGoubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634.
      Scott, J.K., et al. 2001. EMBO J. 20, 767.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₉₀H₁₄₄N₂₀O₂₅
      Chemical formulaC₉₀H₁₄₄N₂₀O₂₅
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetG-protein βγ
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceMyr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      371820-1MG 04055977213447

      Documentation

      G-Protein βγ Binding Peptide, mSIRK(L9A) - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      G-Protein βγ Binding Peptide, mSIRK(L9A) - Calbiochem Certificates of Analysis

      TitleLot Number
      371820

      References

      Reference overview
      Goubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634.
      Scott, J.K., et al. 2001. EMBO J. 20, 767.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-July-2008 RFH
      SynonymsmSIRK(L9A), myr-SIRKALNIAGYPDYD-OH
      DescriptionA cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) that contains a single point mutation (Leu9 to Ala). In contrast to mSIRK (Cat. No. 371818), the mutant peptide is unable to enhance ERK1/2 phosphorylation. Useful as a negative control for mSIRK.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₉₀H₁₄₄N₂₀O₂₅
      Peptide SequenceMyr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Toxicity Standard Handling
      ReferencesGoubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634.
      Scott, J.K., et al. 2001. EMBO J. 20, 767.