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368057 Sigma-AldrichGranzyme B Substrate I, Colorimetric - Calbiochem

Colorimetric substrate for the detection of granzyme B and caspase-8 activity.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Brochures
Data Sheet

Synonyms: Ac-IETD-pNA, Caspase-8 Substrate I

Recommended Products

Overview

Replacement Information

Pricing & Availability

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Description
Overview	Colorimetric substrate for the detection of granzyme B and caspase-8 activity. Cleavage of pNA is monitored colorimetrically at ~405 nm.
Catalogue Number	368057
Brand Family	Calbiochem®
Synonyms	Ac-IETD-pNA, Caspase-8 Substrate I

References
References	Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

Product Information
ATP Competitive	N
Form	White lyophilized solid
Hill Formula	C₂₇H₃₈N₆O₁₂
Chemical formula	C₂₇H₃₈N₆O₁₂
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	Colorimetric substrate for the detection of granzyme B and caspase-8 activity
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Sequence	Ac-Ile-Glu-Thr-Asp-pNA

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Catalogue Number	GTIN
368057-5MG	04055977192155

Documentation

Granzyme B Substrate I, Colorimetric - Calbiochem SDS

Title
Safety Data Sheet (SDS)

Granzyme B Substrate I, Colorimetric - Calbiochem Certificates of Analysis

Title	Lot Number
368057	Enter Lot Number

References

Reference overview
Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	07-July-2008 RFH
Synonyms	Ac-IETD-pNA, Caspase-8 Substrate I
Description	Colorimetric substrate for detection of granzyme B. Cleavage is monitored colorimetrically at ~405 nm.
Form	White lyophilized solid
Chemical formula	C₂₇H₃₈N₆O₁₂
Peptide Sequence	Ac-Ile-Glu-Thr-Asp-pNA
Purity	≥95% by HPLC
Solubility	DMSO (5 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

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