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489350 L-(–)-Norepinephrine-(+)-bitartrate salt monohydrate - CAS 108341-18-0 - Calbiochem

α,β-Adrenergic agonist.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline, 1,2-Benzenediol, 4-[{1R)-2-amino-1-hydroxyethyl]-, (2R,3R)-2,3-dihydroxybutanedioate, hydrate (1:1:1)

Primary Target: α,β-Adrenergic agonist
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      108341-18-0C₈H₁₁NO₃ • C₄H₆O₆•H₂O
      Description
      Overviewα,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.
      Catalogue Number489350
      Brand Family Calbiochem®
      SynonymsR(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline, 1,2-Benzenediol, 4-[{1R)-2-amino-1-hydroxyethyl]-, (2R,3R)-2,3-dihydroxybutanedioate, hydrate (1:1:1)
      References
      ReferencesYang, H., et al. 1996. Hypertension 27, 1277.
      Product Information
      CAS number108341-18-0
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₈H₁₁NO₃ • C₄H₆O₆•H₂O
      Chemical formulaC₈H₁₁NO₃ • C₄H₆O₆•H₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetα,β-Adrenergic agonist
      Purity≥97% by LC-MS
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSDN6750000
      Safety Information
      R PhraseR: 26/27/28-60

      Very toxic by inhalation, in contact with skin and if swallowed.
      May impair fertility.
      S PhraseS: 22-36/37/39-45

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      489350 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      L-(–)-Norepinephrine-(+)-bitartrate salt monohydrate - CAS 108341-18-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      L-(–)-Norepinephrine-(+)-bitartrate salt monohydrate - CAS 108341-18-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      489350

      References

      Reference overview
      Yang, H., et al. 1996. Hypertension 27, 1277.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-February-2020 JSW
      SynonymsR(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline, 1,2-Benzenediol, 4-[{1R)-2-amino-1-hydroxyethyl]-, (2R,3R)-2,3-dihydroxybutanedioate, hydrate (1:1:1)
      Descriptionα,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors.
      FormWhite crystalline solid
      CAS number108341-18-0
      RTECSDN6750000
      Chemical formulaC₈H₁₁NO₃ • C₄H₆O₆•H₂O
      Structure formulaStructure formula
      Purity≥97% by LC-MS
      SolubilityH₂O (1 mg/ml). Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.
      Storage Protect from moisture
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Merck USA index14, 6695
      ReferencesYang, H., et al. 1996. Hypertension 27, 1277.