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SCT017 LuminiCell Tracker™ NIR- Cell Labeling Kit

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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT017
      DescriptionLuminiCell Tracker™ NIR- Cell Labeling Kit
      OverviewNovel aggregation-induced emission (AIE) particles have unique properties. Unlike conventional molecular dyes which may be hindered by aggregation-induced quenching, AIE molecules are loaded and encapsulated in the core of nanoparticles, resulting in high fluorescence intensities with minimal signal quenching, unique spectral attributes, and exceptional signal longevity.

      When compared with quantum dots of similar size under the same excitation and emission conditions, SCT017 Cell Tracker reagent fluorescent signal is 10x brighter, with no observable photobleaching after 30 minutes of continuous laser irradiation.
      Alternate Names
      • Live Cell Imaging Probe
      • Live Cell Fluorescent Tracker
      • NIR Live Cell Tracker
      • Near infrared fluorescent cell tracker
      Background InformationLong-term noninvasive cell tracking by fluorescent probes and quantum dots is increasingly useful to life scientists and biomedical engineers. Current methods used to fluorescently tag cells have been limited by short signal duration, high background autofluorescence or complex and time-consuming molecular cloning manipulations using fluorescent proteins such as GFP.

      LuminiCell Trackers™ are biocompatible organic fluorescent nanoparticles based on Aggregation Induced Emission (AIEdot) technology. Aggregation-induced emission (AIE) molecules emit fluorescence differently than other popular fluorophores such as fluorescent proteins: propeller-shaped AIE fluorogens are non-emissive in solutions but become highly fluorescent upon aggregate formation. As a consequence, LuminiCell Trackers™ have very high fluorescence intensities with minimal signal quenching, allowing live cell fluorescent tagging for up to 10 days in vitro and 21 days in vivo. Such properties make these unique trackers optimal candidates for long interval live cell bioimaging experiments.
      References
      Product Information
      Detection methodFlow cytometry Fluorescent
      FormatLiquid Reagent
      Quality LevelMQ100
      Applications
      Key Applications
      • Cell Based Assays
      • Flow Cytometry
      • Fluorescence
      Application NotesSCT017 contains highly emissive fluorescent organic nanoparticles, designed for rapid labeling of live cells with biocompatibility. These particles can be readily taken up by diverse cell types, often within one hour. Once within cells, these particles demonstrate bright fluorescence with remarkable photostability. and emit durable signal for multiple cell generations with negligible cytotoxicity.

      Labelled cells can be monitored using a variety of fluorescence techniques such as confocal microscopy, multiphoton microscopy and flow cytometry.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at 2 - 8°C, protected from light. Spin vial briefly to collect contents at bottom of vial before opening. Do not freeze.
      Packaging Information
      Material Size1 kit
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT017 04065272208666