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474705 Mevastatin, Sodium Salt - Calbiochem

Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.

Mevastatin, Sodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: HMG-CoA reductase
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474705
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₃H₃₅O₆ · Na

Pricing & Availability

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474705-5MG
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      Description
      OverviewCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays.
      Catalogue Number474705
      Brand Family Calbiochem®
      References
      ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
      Endo, A. 1992. J. Lipid Res. 33, 1569.
      Product Information
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₂₃H₃₅O₆ · Na
      Chemical formulaC₂₃H₃₅O₆ · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      Biological Information
      Primary TargetHMG-CoA reductase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      474705-5MG 04055977185423

      Documentation

      Mevastatin, Sodium Salt - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Mevastatin, Sodium Salt - Calbiochem Certificates of Analysis

      TitleLot Number
      474705

      References

      Reference overview
      Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
      Endo, A. 1992. J. Lipid Res. 33, 1569.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-September-2020 JSW
      DescriptionCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G1 phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).
      FormWhite to off-white solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₃H₃₅O₆ · Na
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (30 mg/ml) or Ethanol (20 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
      Endo, A. 1992. J. Lipid Res. 33, 1569.