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475956 c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem

The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one

Primary Target: c-Myc
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475956
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
403811-55-2C₁₂H₁₁NOS₂

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475956-10MG
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      Description
      OverviewA cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
      Catalogue Number475956
      Brand Family Calbiochem®
      Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
      References
      ReferencesYin, X., et al. 2003. Oncogene 22, 6151.
      Product Information
      CAS number403811-55-2
      ATP CompetitiveN
      DeclarationSold under license of U.S. Patent 7,026,343.
      FormYellow solid
      Hill FormulaC₁₂H₁₁NOS₂
      Chemical formulaC₁₂H₁₁NOS₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetc-Myc
      Purity≥95% by HPLC (sum of two isomers)
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      475956-10MG 04055977184303

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      475956

      References

      Reference overview
      Yin, X., et al. 2003. Oncogene 22, 6151.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
      DescriptionA cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (Effective concentration: 64 µM using c-Myc-transfected Rat1a fibroblasts).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number403811-55-2
      Chemical formulaC₁₂H₁₁NOS₂
      Structure formulaStructure formula
      Purity≥95% by HPLC (sum of two isomers)
      SolubilityDMSO (200 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      ReferencesYin, X., et al. 2003. Oncogene 22, 6151.