Skip to Content
Merck

Key Documents

View All Documentation

104132

Cellvento® ModiFeed Prime COMP

greener alternative

chemically defined cell culture feed, compacted dry powder

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

UNSPSC Code:
41106213
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

500

description

shipped with cooling packs

product line

Cellvento®

form

compacted dry powder

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | mammalian: suitable (suspension)

application(s)

pharma/biopharma processes

greener alternative category

DfS-Developed

storage temp.

2-8°C

General description

Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield. We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product.Click here to view its DfS scorecard.
Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield.The formulation has been specifically designed to provide increased process control and decreased complexity. Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter. As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.

Application

  • Cellvento® ModiFeed Prime COMP has been developed as a feed supplement to be used in combination with the production media, Cellvento® 4CHO COMP and EX-CELL® Advanced CHO, during fed-batch manufacturing processes.
  • It has been designed to support optimal cell growth and high productivity of suspension CHO cell lines such as CHO-K1, CHO-DG44, CHO-S and CHO-GS, including cell lines derived using the CHOZN® platform Fed-batch (batch, perfusion)

Features and Benefits

  • The formulation has been specifically designed to provide increased process control and decreased complexity.
  • Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter.
  • As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.

Preparation Note

Formulated to contain 131.6 grams of powder per liter of medium.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Optimizing Upstream Media and Feeds in Bioprocessing

Why optimize your upstream bioprocess media and feed? This article discusses the why and how of optimizing your media and feed to maximize cell viability and productivity.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

View All Articles

Related Content

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Modifeed Prime DfS scorecard
View All Related Content

Global Trade Item Number

SKUGTIN
1.04132.000504065267458502
1.04132.005004065266468755
1.04132.000104065266432459