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Merck

238813

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

97%

Synonym(s):

Trolox

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About This Item

Empirical Formula (Hill Notation):
C14H18O4
CAS Number:
53188-07-1
Molecular Weight:
250.29
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24854347
EC Number:
258-422-8
Beilstein/REAXYS Number:
1384051
MDL number:
MFCD00006846
Assay:
97%

Key Documents

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InChI key

GLEVLJDDWXEYCO-UHFFFAOYSA-N

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

SMILES string

Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

assay

97%

storage condition

under inert gas

Quality Level

200

Gene Information

rat ... Akr1b1(24192)

mp

187-189 °C (lit.)

functional group

carboxylic acid

storage temp.

2-8°C

Related Categories

General description

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Application

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

238813-5G: + 238813-BULK: + 238813-25G: + 238813-VAR: + 238813-1MG: + 238813-2X1MG: + 238813-1KG: + 238813-1G:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF8384V
WXBF7855V
BCCP1114
WXBF7588V
0000509181

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Jessica Scalzo et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(2), 207-213 (2005-02-23)
We wanted to determine the total antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay; TEAC) of different species and cultivars (strawberry and apple) and to characterize the TEAC among fruits of the same varieties (peach and apricot) but grafted on different
Flavonoids as antioxidants
Jovanovic S, et al.
Journal of the American Chemical Society, 116, 4846-4846 (1994)
Functional Analogues of the Dioxygen Reduction Site in Cytochrome Oxidase:? Mechanistic Aspects and Possible Effects of CuB
Boulatov R, et al.
Journal of the American Chemical Society, 124(40), 11923-11923 (2002)
Dalia Mazor et al.
Biochemical and biophysical research communications, 349(3), 1171-1175 (2006-09-15)
The antioxidant properties of Bucillamine (BUC), a di-thiol compound used for treatment of rheumatoid arthritis (RA) and its possible mode of action, were investigated. BUC exhibits potent antioxidant activity similar to those of trolox and ascorbic acid. It reduces the
C Giulivi et al.
Archives of biochemistry and biophysics, 303(1), 152-158 (1993-05-15)
The reactivity of Trolox C, a water-soluble analog of vitamin E, toward protein radicals formed during the oxidation of metmyoglobin and the therefrom derived molecular products was examined in terms of the ability of the phenolic antioxidant to prevent specific
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