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Merck

760110

4-Cyano-4-[(dodecylsulfanylthiocarbonyl)sulfanyl]pentanol

Synonym(s):

Dodecyl Thiol Cyano Thiol

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About This Item

Empirical Formula (Hill Notation):
C19H35NOS3
Molecular Weight:
389.68
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
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assay

≥96.5% (HPLC)

Quality Level

form

solid or liquid (Powder or Solid or Crystals or Chunk(s) or Semi-solid or Liquid)

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCSC(=S)SC(C)(CCCO)C#N

InChI

1S/C19H35NOS3/c1-3-4-5-6-7-8-9-10-11-12-16-23-18(22)24-19(2,17-20)14-13-15-21/h21H,3-16H2,1-2H3

InChI key

SAFBIHFUHZPVOZ-UHFFFAOYSA-N

General description

Reversible addition-fragmentation chain transfer (RAFT) polymerisation is used to produce narrow polydispersity polymers of complex architecture. 4-Cyano-4-[(dodecylsulfanylthiocarbonyl)sulfanyl]pentanol is an hydroxyl functionalised trithiocarbonate RAFT agent.It is used as a dual initiator for RAFT and ring opening polymerisation to form well-defined block copolymers. They have good control of polymerisation for a wide range of vinyl monomers.

Application

Initiator for RAFT and ring opening polymerisation of block copolymers derived from vinyl monomers of styrene, metacryalte, acrylamide and cyclic monomers.

Features and Benefits

Good hydrolytic stability, suitable for a wide range of monomers and reaction conditions.


pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Substances Subject to be Notified Names

ishl_notified

760110-5G:4.548173311548E12 + 760110-1G:4.548173311531E12

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Protocols

ウォーリック大学のProf. Dave Haddletonの研究グループによって実証された、ATRPによる重合。

RAFT(可逆的付加-開裂連鎖移動)重合によるPMMAおよびPVAcの典型的な重合手順をご紹介します。

We present an article about RAFT, or Reversible Addition/Fragmentation Chain Transfer, which is a form of living radical polymerization.

View All Protocols

Articles

The modification of biomacromolecules, such as peptides and proteins, through the attachment of synthetic polymers has led to a new family of highly advanced biomaterials with enhanced properties.

ペプチドやタンパク質のような生体高分子に合成ポリマーを結合させて修飾することで、特性が強化された極めて高度な新しい種類の生体材料が得られています。

Micro Review:RAFT(可逆的付加/開裂連鎖移動)重合


Thiocarbonylthio compounds (SC (Z) SR) in free radical polymerization with reversible addition-fragmentation chain transfer (RAFT polymerization).
Chiefari, J., Mayadunne, R. T., Moad, C. L., Moad, G., Rizzardo, E., Postma, A., & Thang, S. H.
Macromolecules, 36(7), 2273-2283 (2003)
One-step synthesis of block copolymers using a hydroxyl-functionalized trithiocarbonate RAFT agent as a dual initiator for RAFT polymerization and ROP
Kang, H. U., Yu, Y. C., Shin, S. J., & Youk, J. H.
Journal of Polymer Science Part A: Polymer Chemistry, 51(4), 774-779 (2013)
RAFT Agent Design and Synthesis
Keddie, D. J.; et al.
Macromolecules, 45, 5321-5342 (2012)