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Merck

799661

Fe/ppm Pd for Suzuki-Miyaura Cross-Couplings

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About This Item

EC Number:
231-729-4
UNSPSC Code:
12161600
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form

powder, crystals or chunks

reaction suitability

core: iron, reaction type: Cross Couplings, reagent type: catalyst

Application

Nanoparticles (NPs) of this material contain parts per million (ppm) levels of Pd. The NPs can catalyze Suzuki-Miyaura (SM) reactions, including cases involving highly challenging reaction partners. Nano micelles are employed to both solubilize and deliver the reaction partners to the Fe/ppm Pd catalyst resulting in C-C bond formation.


pictograms

CorrosionExclamation mark

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

13 - Non Combustible Solids


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

799661-BULK: + 799661-VAR: + 799661-500MG:4548174007525

jan



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Related Content

Designer surfactants enable diverse transformations like Suzuki-Miyaura, Olefin Metathesis, and 1,4-Addition to Enones in water by Prof. Bruce Lipshutz.


Sachin Handa et al.
Science (New York, N.Y.), 349(6252), 1087-1091 (2015-09-05)
Most of today's use of transition metal-catalyzed cross-coupling chemistry relies on expensive quantities of palladium (Pd). Here we report that nanoparticles formed from inexpensive FeCl3 that naturally contains parts-per-million (ppm) levels of Pd can catalyze Suzuki-Miyaura reactions, including cases that
Switching from organic solvents to water at an industrial scale.
Parmentier M, et al.
Current opinion in green and sustainable chemistry., 7, 13-17 (2017)
When Does Organic Chemistry Follow Nature?s Lead and ?Make the Switch?.
Lipshutz B H
The Journal of Organic Chemistry, 82(6), 2806-2816 (2017)