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Merck

104132

Cellvento® ModiFeed Prime COMP

greener alternative

chemically defined cell culture feed

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UNSPSC Code:
41106213

Key Documents

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description

shipped with cooling packs

product line

Cellvento®

form

dry powder

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | mammalian: suitable (suspension)

greener alternative category

DfS-Developed

storage temp.

2-8°C

Quality Level

500

Related Categories

General description

Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield.The formulation has been specifically designed to provide increased process control and decreased complexity. Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter. As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives . This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

Application

Cellvento® ModiFeed Prime COMP has been developed as a feed supplement to be used in combination with the production media, Cellvento® 4CHO COMP and EX-CELL® Advanced CHO, during fed-batch manufacturing processes. It has been designed to support optimal cell growth and high productivity of suspension CHO cell lines such as CHO-K1, CHO-DG44, CHO-S and CHO-GS, including cell lines derived using the CHOZN® platform Fed-batch (batch, perfusion)

Preparation Note

Formulated to contain 131.6 grams of powder per liter of medium.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Poisonous substance

pdsc

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Optimizing Upstream Media and Feeds in Bioprocessing

Why optimize your upstream bioprocess media and feed? This article discusses the why and how of optimizing your media and feed to maximize cell viability and productivity.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

Direct upstream monitoring with Raman ready-to-use models

Streamline upstream process monitoring with embedded Raman ready-to-use models for easy implementation and improved process understanding

See All

Related Content

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

Application Note Optimizing Feed Strategies
Improving fed-batch yields by combining EX-CELL® Advanced and Cellvento® cell culture media portfolios

Global Trade Item Number

SKUGTIN
1.04132.000504065267458502
1.04132.005004065266468755
1.04132.000104065266432459

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