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Merck

345759

Anti-Ganglioside GM2 Rabbit pAb

liquid, Calbiochem®

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
-
Application:
—
Citations:
4

Key Documents

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biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity (predicted by homology)

all

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:200)
TLC Immunoblotting (1:100, colorimetric))

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

General description

Anti-Ganglioside GM₂, rabbit polyclonal recognizes ganglioside GM₂ in a wide variety of species. It is validated for use in ELISA and TLC immunoblotting.
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the GM2 ganglioside.
Recognizes ganglioside GM2.

Immunogen

purified, human ganglioside GM₂

Application

ELISA (1:200)

TLC Immunoblotting (1:100, colorimetric)

Other Notes

Does not cross-react with other carbohydrate epitopes. Variables associated with assay conditions will dictate the optimal working dilution.
Yoshino, H., et al. 1993. J. Neurochem. 61, 658.
Kusunoki, S., et al. 1987. Neurology 37, 1795.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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wgk

WGK 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

345759-100UL: + 345759-UL:

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yuehong Chen et al.
Journal of molecular medicine (Berlin, Germany), 96(12), 1359-1373 (2018-10-21)
Tay-Sachs disease (TSD) is a lethal lysosomal storage disease (LSD) caused by mutations in the HexA gene, which can lead to deficiency of β-hexosaminidase A (HexA) activity and consequent accumulation of its substrate, GM2 ganglioside. Recent reports that progranulin (PGRN)
Aleksandra Somogyi et al.
International journal of molecular sciences, 19(2) (2018-02-23)
Juvenile neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene. Most JNCL patients exhibit a 1.02 kb genomic deletion removing exons 7 and 8 of this gene, which results in a truncated CLN3 protein carrying an aberrant
Erica Tagliatti et al.
Immunity, 57(1), 86-105 (2024-01-02)
Triggering receptor expressed on myeloid cells 2 (Trem2) is a myeloid cell-specific gene expressed in brain microglia, with variants that are associated with neurodegenerative diseases, including Alzheimer's disease. Trem2 is essential for microglia-mediated synaptic refinement, but whether Trem2 contributes to
Meredith K Loth et al.
Neurobiology of disease, 85, 174-186 (2015-11-08)
Translocator protein (18 kDa), formerly known as the peripheral benzodiazepine receptor (PBR), has been extensively used as a biomarker of active brain disease and neuroinflammation. TSPO expression increases dramatically in glial cells, particularly in microglia and astrocytes, as a result

Global Trade Item Number

SKUGTIN
345759-100ULCN04055977193947

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