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Merck

407710

α-Iodoacetamide

≥99% (HPLC), crystalline solid, cysteine protease inhibitor, Calbiochem®

Synonym(s):

α-Iodoacetamide

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About This Item

Empirical Formula (Hill Notation):
C2H4INO
CAS Number:
144-48-9
Molecular Weight:
184.96
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00008028

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Product Name

α-Iodoacetamide, α-Iodoacetamide, CAS 144-48-9, is an irreversible inhibitor of several cysteine proteases.

SMILES string

ICC(=O)N

InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI key

PGLTVOMIXTUURA-UHFFFAOYSA-N

description

RTECS - AC4200000

assay

≥99% (HPLC)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

methanol: 1:20, DMF: soluble, ethanol: soluble, water: soluble

shipped in

ambient

storage temp.

−20°C

Quality Level

200

Related Categories

General description

An irreversible inhibitor of several cysteine proteases. Useful for alkylating cysteine and methionine residues.

Biochem/physiol Actions

Cell permeable: no
Primary Target
cysteine proteases
Product does not compete with ATP.
Reversible: no

Preparation Note

Unstable in solution; reconstitute just prior to use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic (F)

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

407710-0GM: + 407710-GM: + 407710-500GM: + 407710-25GM:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The serotonin 5-HT2A receptor (5-HT2AR) is a member of the GPCR family that is important for various neurological functions and whose dysregulation causes many mental health disorders. Structural investigations of 5-HT2AR require the production of functionally active receptors expressed from

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Global Trade Item Number

SKUGTIN
407710-25GMCN04055977211498

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