Skip to Content
Merck

70856

RNase A Solution

Convenient solution for selective degradation of RNA

Synonym(s):

RNase A Enzyme

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

NACRES:
NA.54
UNSPSC Code:
12352202
Concentration:
10 mg/mL

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

solution

manufacturer/tradename

Novagen®

storage condition

OK to freeze

concentration

10 mg/mL

technique(s)

DNA purification: suitable

shipped in

ambient

storage temp.

10-30°C

Looking for similar products? Visit Product Comparison Guide

General description

RNase A Solution is a convenient alternative to powdered RNase A. It is a highly purified preparation of bovine pancreatic ribonuclease A suitable for use in selective removal of RNA. It has been pretreated to remove DNase I and is suitable to remove RNA contamination during plasmid and genomic DNA purification procedures. Supplied at a concentration of 10 mg/ml in 10 mM Tris-HCl, 1 mM EDTA, 50% glycerol, pH 7.5.

Application

RNase A Solution has been used:
  • in cell cycle profiling of embryonic mouse neuroectodermal cells (NE-4C)
  • in the digestion of RNA for extraction of DNA from human osteosarcoma cell lines for chromatin immunoprecipitation (ChIP) assays
  • to treat control adult and embryonic thymi cells during staining
  • to remove RNA from affibody–mRNA fusion clones before clone screening

Biochem/physiol Actions

RNaseA is an endoribonuclease that catalyzes the degradation of phosphodiester linkages with a pyrimidine base at the 3′ -position on single-stranded RNA via, transphosphorylation and hydrolysis mechanism.

Legal Information

NOVAGEN is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H334

Hazard Classifications

Resp. Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

70856-ML: + 70856-3: + 70856-1ML:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth
Jennifer E C, et al.
Nature Communications (2019)
Neurotrophic properties and the de novo peptide sequencing of edible bird's nest extracts
Yew M Y, et al.
Food Bioscience, 32, 100466-100466 (2019)
Jiajun Zhang et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(11), 2681-2692 (2020-01-16)
Malignancy of cancer cells depends on the active transcription of tumor-associated genes. Recently, unique clusters of transcriptional enhancers, termed super-enhancers, have been reported to drive the expression of genes that define cell identity. In this study, we characterized specific super-enhancer-associated

Global Trade Item Number

SKUGTIN
70856-3CN04055977272666

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service