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Merck

MABN736

Anti-NEGR1, clone 4H2.1 Antibody

clone 4H2.1, from mouse

Synonym(s):

Neuronal growth regulator 1, IgLON family member 4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4H2.1, monoclonal
Application:
IHC, WB
Citations:
-

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

4H2.1, monoclonal

species reactivity

rat, human

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_776169

UniProt accession no.

Q7Z3B1

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... NEGR1(257194)

General description

Neuronal growth regulator 1 (NEGR1) is also called IgLON family member 4. NEGR1 belongs to the immunoglobulin superfamily and is thought to be involved in cell-adhesion. NEGR1 possibly functions as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.
~50 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human NEGR1.

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected NEGR1 in human cerebellum and rat cerebral cortex tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
This Anti-NEGR1, clone 4H2.1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of NEGR1.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected NEGR1 in 10 µg of human hippocampus tissue lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.
Replaces: MABN1072

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

MABN736:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
MABN73604053252984938

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