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Merck

28-3460

Sodium nitrite

JIS special grade, ≥98.5%

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About This Item

Linear Formula:
NaNO2
CAS Number:
Molecular Weight:
69.00
UNSPSC Code:
12352302
PubChem Substance ID:
EC Number:
231-555-9
MDL number:
Assay:
≥98.5%
Grade:
JIS special grade
Form:
solid
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InChI key

LPXPTNMVRIOKMN-UHFFFAOYSA-M

InChI

1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1

SMILES string

[Na+].[O-]N=O

grade

JIS special grade

vapor pressure

<0.000 hPa ( 25 °C)

assay

≥98.5%

form

solid

autoignition temp.

914 °F

availability

available only in Japan

pH

9

mp

271 °C (lit.)

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Ox. Sol. 3

Storage Class

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Group 1: Oxidizing solids + Nitrites + Hazardous rank I + 1st oxidizing solid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

28-3460-2-25G-J: + 28-3460-5-500G-J: + 28-3460-BULK-J:

jan


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Lucas C Pinheiro et al.
Free radical biology & medicine, 53(4), 701-709 (2012-06-23)
The new pathway nitrate-nitrite-nitric oxide (NO) has emerged as a physiological alternative to the classical enzymatic pathway for NO formation from l-arginine. Nitrate is converted to nitrite by commensal bacteria in the oral cavity and the nitrite formed is then
Peter J Rix et al.
Clinical pharmacokinetics, 54(3), 261-272 (2014-11-26)
The efficacy of nebulized sodium nitrite (AIR001) has been demonstrated in animal models of pulmonary arterial hypertension (PAH), but it was not known if inhaled nitrite would be well tolerated in human subjects at exposure levels associated with efficacy in
Rustem F Dautov et al.
Nitric oxide : biology and chemistry, 40, 36-44 (2014-05-27)
Previous studies in non-human blood vessels and in platelets have demonstrated that under hypoxic conditions release of NO from nitrite (NO2(-)) is potentiated by deoxyhaemoglobin. In the current study, we characterized hypoxic potentiation of NO2(-) effects in human vasculature and
Edward H Oldfield et al.
Journal of neurosurgery, 119(3), 634-641 (2013-05-28)
Intravenous sodium nitrite has been shown to prevent and reverse cerebral vasospasm in a primate model of subarachnoid hemorrhage (SAH). The present Phase IIA dose-escalation study of sodium nitrite was conducted to determine the compound's safety in humans with aneurysmal
Borja Ibáñez et al.
Journal of the American College of Cardiology, 65(14), 1454-1471 (2015-04-11)
The damage inflicted on the myocardium during acute myocardial infarction is the result of 2 processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the last 3 decades, therapies to reduce ischemic injury (mainly reperfusion strategies) have been widely incorporated into

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