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Merck

05164

(Aminomethyl)phosphonic acid

PESTANAL®, analytical standard

Synonym(s):

AMPA

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About This Item

Linear Formula:
NH2CH2P(O)(OH)2
CAS Number:
1066-51-9
Molecular Weight:
111.04
UNSPSC Code:
77101502
NACRES:
NA.24
PubChem Substance ID:
329747650
MDL number:
MFCD00008105
Beilstein/REAXYS Number:
1701219

Key Documents

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InChI

1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)

InChI key

MGRVRXRGTBOSHW-UHFFFAOYSA-N

SMILES string

NCP(O)(O)=O

grade

analytical standard

product line

PESTANAL®

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤3.0% water (calc. from elemental analysis)

application(s)

agriculture
environmental

format

neat

Quality Level

100

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Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

05164-VAR: + 05164-50MG: + 05164-BULK:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP2825
BCCM8497
BCCM2803
BCCL2136
BCCK3466

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Seonil Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3122-3127 (2015-02-26)
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation
Philip Jean-Richard Dit Bressel et al.
PloS one, 9(11), e111699-e111699 (2014-11-05)
The lateral habenula (LHb) is a small epithalamic structure that projects via the fasciculus retroflexus to the midbrain. The LHb is known to modulate midbrain dopamine (DA) neurons, including inhibition of ventral tegmental area (VTA) neurons via glutamatergic excitation of
Mary L Huff et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 861-873 (2014-09-27)
Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved in generating reward-prediction
Einar Ö Einarsson et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(2), 480-487 (2014-08-06)
After acquisition, hippocampus-dependent memories undergo a systems consolidation process, during which they become independent of the hippocampus and dependent on the anterior cingulate cortex (ACC) for memory expression. However, consolidated remote memories can become transiently hippocampus-dependent again following memory reactivation.
W Zhou et al.
European psychiatry : the journal of the Association of European Psychiatrists, 29(7), 419-423 (2013-12-11)
Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ketamine's antidepressant effects are probably attributed to the activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
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