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Merck

27715

L-(+)-Lactic acid

80%, liquid

Synonym(s):

(S)-2-Hydroxypropionic acid, Sarcolactic acid

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
79-33-4
Molecular Weight:
90.08
NACRES:
NA.21
PubChem Substance ID:
57648269
UNSPSC Code:
12352100
MDL number:
MFCD00064266
Beilstein/REAXYS Number:
1720251
Assay:
80%
Form:
liquid

Key Documents

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Product Name

L-(+)-Lactic acid, 80%

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

SMILES string

C[C@H](O)C(O)=O

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

assay

80%

form

liquid

ign. residue

≤0.1% (as SO4)

solubility

water: soluble(lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤100 mg/kg, Fe: ≤10 mg/kg

antibiotic activity spectrum

Gram-negative bacteria

mode of action

cell membrane | interferes

Quality Level

100

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Related Categories

Application


  • Pharmaceutical and biomaterial applications: L-(+)-Lactic acid enhances M2 macrophage polarization through regulation of the PCK2/AMPK/mTOR signaling pathway in poly-L-lactic acid membranes, indicating its vital role in biomedicine and materials science (Tang et al., 2024).

  • Agricultural biotechnology: The induction of defense responses in tobacco against Phytophthora nicotianae by L-(+)-Lactic acid underscores its potential application in agricultural biotechnology for plant disease management (Yan et al., 2024).



Biochem/physiol Actions

Use as a substrate for the lactic acid dehydrogenase enzymes.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1

supp_hazards

EUH071

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

230.0 °F

flash_point_c

110 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

27715-VAR-R: + 27715-30KG-R: + 27715-6X1L-R: + 27715-BULK-R: + 27715-1L-R: + 27715-25KG-R:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB3101
STBL3141
STBK8134
STBK4532
STBK1312

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Synthesis and characterization of pH-sensitive hydrogels based on chitosan and D, L-lactic acid.
Qu X, et al.
Journal of Applied Polymer Science, 74(13), 3193-3202 (1999)
Swelling and hydrolytic degradation of poly (D, L-lactic acid) in aqueous solutions.
Proikakis C S, et al.
Polymer Degradation and Stability, 91(3), 614-619 (2006)
Recovery of L-(+)-lactic acid by anion exchange resin Amberlite IRA-400.
Cao X, et al.
Biochemical Engineering Journal, 11(2), 189-196 (2002)
Carlos Carmona-Fontaine et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(11), 2934-2939 (2017-03-02)
The genetic and phenotypic diversity of cells within tumors is a major obstacle for cancer treatment. Because of the stochastic nature of genetic alterations, this intratumoral heterogeneity is often viewed as chaotic. Here we show that the altered metabolism of
S Walenta et al.
Current medicinal chemistry, 11(16), 2195-2204 (2004-07-29)
A number of studies have demonstrated that malignant transformation is associated with an increase in glycolytic flux and in anaerobic and aerobic cellular lactate excretion. Using quantitative bioluminescence imaging in various primary carcinomas in patients (uterine cervix, head and neck
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