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Merck

33034

L-Ascorbic acid

ACS reagent grade, 99.7-100.5% (oxidimetric), solid, suitable for IR spectroscopy, puriss. p.a., reag. ISO, Ph. Eur.

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
NACRES:
NA.21
PubChem Substance ID:
57648740
UNSPSC Code:
12352100
EC Number:
200-066-2
MDL number:
MFCD00064328
Beilstein/REAXYS Number:
84272

Key Documents

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Product Name

L-Ascorbic acid, puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

grade

ACS reagent, puriss. p.a.

agency

Ph. Eur., USP/NF, reag. ISO

assay

99.7-100.5% (oxidimetric)

form

solid

optical activity

[α]20/D +20.5 to +21.5°, c = 10% in H2O

technique(s)

IR spectroscopy: suitable

impurities

related substances, in accordance (HPLC), ≤0.001% heavy metals (by ICP-OES)

ign. residue

≤0.05% (as SO4)

loss

≤0.1% loss on drying, 105 °C

pH

2.1-2.6 (20 °C, 5%)

mp

190-192 °C ((decomp)) (lit.), 190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤20 mg/kg

cation traces

As: ≤1 mg/kg, Cu: ≤5 mg/kg, Fe: ≤2 mg/kg, Pb: ≤5 mg/kg, Zn: ≤10 mg/kg

suitability

complies for appearance of solution, passes test for identity (IR)

application(s)

cell analysis

functional group

ester, hydroxyl, ketone

Quality Level

200

Gene Information

human ... SLC23A2(9962)

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General description

L-Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. Benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, hyperpigmentation, skin protection, anti-aging, iron absorption, and red blood cell production. It is also useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

L-Ascorbic acid has been used as an analytical interfering substance in glycated albumin (GA) enzymatic assay.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

33034-6X25G: + 33034-25G: + 33034-6X100G: + 33034-1.5KG: + 33034-6X1KG: + 33034-25KG: + 33034-100G: + 33034-BULK: + 33034-6X250G: + 33034-250G: + 33034-VAR: + 33034-1KG:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
STBL0764
SDBB1734
STBK8230
STBK6828
STBK6827

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Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Testa R, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 1(2), 162-171 (2016)
T R Tickner et al.
Clinica chimica acta; international journal of clinical chemistry, 85(2), 125-129 (1978-04-17)
A new colorimetric method for the assay of biliverdin in biological fluids is described. The method, based upon the reaction of biliverdin with barbituric acid, offers improved sensitivity and selectivity when compared to direct spectrophotometric measurements. Using this method biliverdinaemia
A family of mammalian NaI[plus]I-dependent L-ascorbic acid transporters.
Tsukaguchi H, et al.
Nature, 673(1), 70-75 (1999)
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)
Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Carita AC, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 31(2), 102117-102117 (2019)
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