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Merck

71631

Sodium bicarbonate

tested according to Ph. Eur.

Synonym(s):

Natrii hydrogenocarbonas, Sodium hydrogen carbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
UNSPSC Code:
12352300
NACRES:
NA.21
PubChem Substance ID:
329763379
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
MFCD00003528

Key Documents

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Product Name

Sodium bicarbonate, tested according to Ph. Eur.

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

SMILES string

[Na+].OC([O-])=O

Quality Level

200

agency

tested according to Ph. Eur.

assay

99.0-101.0%

form

solid

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

water: soluble 50 g/L

density

2.16 g/mL at 25 °C (lit.)

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Application


  • Lyophilized rumen fluid as a ruminal fermentation modifier in high grain-fed acidotic goats.: This research examines the effects of sodium bicarbonate on the rumen fluid of goats, particularly in acidosis prevention under high grain diets. It underscores its importance in veterinary science and animal nutrition, providing a preventive measure against digestive disorders in livestock (A Ruba Nanthini et al., 2024).

  • Response of photosynthetic characteristics and antioxidant system in the leaves of safflower to NaCl and NaHCO(3).: This paper focuses on the biochemical responses of safflower leaves to sodium bicarbonate and sodium chloride treatments. The findings highlight how sodium bicarbonate can mitigate salt stress effects, enhancing understanding of plant physiology under stress conditions (Song L et al., 2024).

  • Atomic force microscopy in mechanical measurements of single nanowires.: In this study, sodium bicarbonate is used in preparing samples for atomic force microscopy, demonstrating its utility in high-precision scientific measurements. The research enhances our understanding of material properties at the nanoscale, crucial for developing nanotechnology applications (Pruchnik BC et al., 2024).

Biochem/physiol Actions

Sodium bicarbonate can be used to treat salicylate poisoning.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

71631-BULK: + 71631-1KG: + 71631-VAR: + 71631-25KG: + 71631-5KG: + 2550004:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6322
BCCN0938
BCCM8213
BCCL9952
BCCL9348

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Salicylate toxicity from genital exposure to a methylsalicylate-containing rubefacient
Thompson TM, et al.
The Western Journal of Medicine, 17(2), 181-181 (2016)
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Michael Haase et al.
PLoS medicine, 10(4), e1001426-e1001426 (2013-04-24)
Preliminary evidence suggests a nephroprotective effect of urinary alkalinization in patients at risk of acute kidney injury. In this study, we tested whether prophylactic bicarbonate-based infusion reduces the incidence of acute kidney injury and tubular damage in patients undergoing open
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