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Merck

94563

Dimethyl sulfoxide

analytical standard

Synonym(s):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
UNSPSC Code:
12191502
NACRES:
NA.24
PubChem Substance ID:
329770363
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
MFCD00002089

Key Documents

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InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

grade

analytical standard

Quality Level

100

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.95% (GC)

autoignition temp.

573 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

42 %, 63 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

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Related Categories

General description

Dimethyl Sulfoxide (DMSO) contains both highly polar and apolar groups, which impart it an amphipathic character. It can dissolve in both aqueous and organic solvents. It is a commonly used solvent in hydrophobic pharmaceutical agents, exhibiting effective hydroxyl radical scavenging ability.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

DMSO may be used as an analytical standard for the determination of the analyte in environmental samples by gas chromatography (GC) technique.
Dimethyl sulfoxide may be used as a molecular probe in the detection and analysis of hydroxyl radicals generated in advanced oxidation processes using high performance liquid chromatography(HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

94563-BULK-F: + 94563-1ML-F: + 94563-5ML-F: + 94563-10ML-F: + 94563-VAR-F:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1567
BCCM7796
BCCL5307
BCCM3813
BCCH9238

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Determination of hydroxyl radicals in advanced oxidation processes with dimethyl sulfoxide trapping and liquid chromatography
Tai C, et al.
Analytica Chimica Acta, 527, 73-80 (2004)
Determination of hydroxyl radicals in advanced oxidation processes with dimethyl sulfoxide trapping and liquid chromatography
Tai C, et al.
Analytica Chimica Acta, 527(1), 73-80 (2004)
Phillip McDonagh et al.
Veterinary microbiology, 174(3-4), 438-447 (2014-12-04)
Feline infectious peritonitis (FIP), a feline coronavirus (FCoV) induced disease, is almost invariably fatal with median life expectancy measured in days. Current treatment options are, at best, palliative. The objectives of this study were to evaluate a panel of nineteen
C F Brayton
The Cornell veterinarian, 76(1), 61-90 (1986-01-01)
Dimethyl sulfoxide (DMSO) is a very simple compound that has stimulated much controversy in the scientific and popular literature. Fig. 1 It is an aprotic solvent. Therapeutic and toxic agents that are not soluble in water are often soluble in
Nuno C Santos et al.
Biochemical pharmacology, 65(7), 1035-1041 (2003-03-29)
DMSO is an amphipathic molecule with a highly polar domain and two apolar methyl groups, making it soluble in both aqueous and organic media. It is one of the most common solvents for the in vivo administration of several water-insoluble
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