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Merck

49781

Glycerol solution

greener alternative

83.5-89.5% (T)

Synonym(s):

1,2,3-Propanetriol

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About This Item

Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
56-81-5
Molecular Weight:
92.09 (anhydrous basis)
UNSPSC Code:
50161901
NACRES:
NA.28
PubChem Substance ID:
57651222
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722
Assay:
83.5-89.5% (T)
Technique(s):
MALDI-MS: suitable
Bp:
182 °C/20 mmHg (lit.)

Key Documents

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InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

SMILES string

OCC(O)CO

assay

83.5-89.5% (T)

form

viscous liquid

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

MALDI-MS: suitable

impurities

10.5-16.5% water

ign. residue

≤0.01% (as SO4)

bp

182 °C/20 mmHg (lit.)

density

1.252 g/mL at 25 °C (lit.)

greener alternative category

Aligned

Quality Level

200

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General description

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

Application

Glycerol solution has been used:
  • in the preparation of blood mimicking fluid
  • in epidermis mimicking films
  • as a constituent of nuclei storage buffer

Biochem/physiol Actions

Glycerol has been used as
  • a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
  • a fuel during designing enzymatic biofuel cell.
  • a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
  • a matrix for fast atom bombardment MS.
  • may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.
Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Other Notes

Substrate for the assay of glycerokinase; glycerol dehydratase; glycerol oxidase

wgk

WGK 1

ppe

Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

49781-5L: + 49781-6X1L: + 49781-1L: + 49781-500ML: + 49781-VAR: + 49781-BULK:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7234
BCCN7233
BCCN1879
BCCM4358
BCCL8995

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Automated end-to-end blood testing at the point-of-care: Integration of robotic phlebotomy with downstream sample processing
Balter ML, et al.
Technology, 1-8 (2018)
Glycerol oxidase from Aspergillus japonicus.
T Uwajima et al.
Methods in enzymology, 89 Pt D, 243-248 (1982-01-01)
Multilayered tissue mimicking skin and vessel phantoms with tunable mechanical, optical, and acoustic properties
Chen AI, et al.
Medical Physics, 43(6), 3117-3131 (2016)
Glycerol dehydratase from Aerobacter aerogenes.
B C Johnson et al.
Methods in enzymology, 42, 315-323 (1975-01-01)
H.U. Bergmeyer, ed.
Methods of Enzymatic Analysis, 2, 216-216 (1983)
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