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Merck

63535

Manganese(II) chloride tetrahydrate

BioUltra, Molecular Biology, ≥99.0% (KT)

Synonym(s):

Manganese chloride tetrahydrate, Manganese dichloride tetrahydrate, MnCl2.4H2O

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About This Item

Linear Formula:
MnCl2 · 4H2O
CAS Number:
13446-34-9
Molecular Weight:
197.91
EC Number:
231-869-6
MDL number:
MFCD00149792
NACRES:
NA.25
PubChem Substance ID:
57651943
UNSPSC Code:
12352302
Assay:
≥99.0% (KT)
Grade:
Molecular Biology
Solubility:
H2O: 0.5 M at 20 °C, clear, colorless

Key Documents

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InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

SMILES string

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

grade

Molecular Biology

product line

BioUltra

assay

≥99.0% (KT)

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

pH

4-6 (25 °C, 0.5 M in H2O)

mp

58 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

sulfate (SO42-): ≤50 mg/kg

λ

0.5 M in H2O

UV absorption

λ: 260 nm Amax: 0.01, λ: 280 nm Amax: 0.01

Quality Level

200

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Other Notes

In the tailing of DNA - MnCl2 buffer recommended for dC and dG tailing; In reverse transcription of RNA with thermostable DNA polymerase

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Brain

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

63535-250G-F:4548174003220 + 63535-50G-F:4548174003237 + 63535-BULK-F: + 63535-VAR-F:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3281
BCCM5039
BCCL6420
BCCH2663
BCCJ4597

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Nicholas Sofos et al.
Molecular cell, 79(5), 741-757 (2020-07-31)
Cmr-β is a type III-B CRISPR-Cas complex that, upon target RNA recognition, unleashes a multifaceted immune response against invading genetic elements, including single-stranded DNA (ssDNA) cleavage, cyclic oligoadenylate synthesis, and also a unique UA-specific single-stranded RNA (ssRNA) hydrolysis by the
T W Myers et al.
Biochemistry, 30(31), 7661-7666 (1991-08-06)
A recombinant DNA polymerase derived from the thermophilic eubacterium Thermus thermophilus (Tth pol) was found to possess very efficient reverse transcriptase (RT) activity in the presence of MnCl2. Many of the problems typically associated with the high degree of secondary
Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis.
G Deng et al.
Methods in enzymology, 100, 96-116 (1983-01-01)
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
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