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Merck

C5135

Castor Oil, Ethoxylated

pH range 6.0-8.0

Synonym(s):

Cremophor® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil

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About This Item

CAS Number:
61791-12-6
UNSPSC Code:
12161902
NACRES:
NA.25
MDL number:
MFCD00130879

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SMILES string

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

description

non-ionic

form

liquid

mol wt

~2500 g/mol

pH range

6.0-8.0

HLB

12 - 14

application(s)

sample preservation

Quality Level

200

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General description

Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.

Application

Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

Biochem/physiol Actions

Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Other Notes

A derivative of castor oil and ethylene oxide.

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable

ppe

Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

C5135-100G: + C5135-500G: + C5135-BULK: + C5135-VAR: + C5135-1KG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN9279
BCCN1173
BCCL7415
BCCL7416
BCCM3065

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The Annals of Thoracic Surgery, 66, 1618-1618 (1998)
A nonionic polyethylene oxide (PEO) surfactant model: experimental and molecular dynamics studies of Kolliphor EL
Suys EJA, et al.
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Ikegaya Y
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M Batisse-Lignier et al.
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