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Merck

EDFS

Ethylenediaminetetraacetic acid iron(III) sodium salt

powder

Synonym(s):

EDTA iron(III) sodium salt, Edathamil, Komplexon II

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About This Item

Linear Formula:
C10H12N2NaFeO8
CAS Number:
Molecular Weight:
367.05
NACRES:
NA.77
PubChem Substance ID:
EC Number:
239-802-2
MDL number:
UNSPSC Code:
12352116
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biological source

synthetic (organic)

Quality Level

agency

suitable for SM 5210

form

powder

composition

Iron, 13.7-18.7% ICP , Sodium, 5.6-7.9% ICP

reaction suitability

reagent type: chelator

concentration

≥67.5% (EDTA titration)

pH

4.5

mp

80 °C

solubility

water: 50 mg/mL, clear to slightly hazy, yellow to brown

storage temp.

room temp

SMILES string

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

InChI key

MKWYFZFMAMBPQK-UHFFFAOYSA-J

Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. Iron-EDTA enhances damage due to reactive oxygen species, such as depletion of reduced glutathione, formation of methemoglobin, and lipid peroxidation.

Legal Information

Komplexon is a trademark of CU Chemie Uetikon AG


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Related Content

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.


Natasha T Forester et al.
Molecular plant-microbe interactions : MPMI, 32(10), 1324-1335 (2019-05-21)
In ascomycetes and basidiomycetes, iron-responsive GATA-type transcriptional repressors are involved in regulating iron homeostasis, notably to prevent iron toxicity through control of iron uptake. To date, it has been unknown whether this iron regulator contributes toward mutualistic endosymbiosis of microbes
Barbara Troesch et al.
The Journal of nutrition, 141(5), 822-827 (2011-03-25)
The absorption profile of iron fortificants may be a determinant of their ability to generate nontransferrin-bound iron (NTBI) and, thus, their potential safety. Ferrous iron may be absorbed more rapidly than chelated ferric iron, but differences at the fortification level
Zhenyu Yang et al.
Maternal & child nutrition, 7 Suppl 3, 123-128 (2011-10-05)
As a highly bioavailable iron compound, sodium iron (iii) ethylenediaminetetraacetate (NaFeEDTA) has been recommended as a food additive for fortification. The amount of a food additive that can be ingested daily over a lifetime without appreciable health risk is termed