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Merck

F1141

Bovine Fibronectin

from bovine plasma, liquid, suitable for cell culture

Synonym(s):

Fibronectin

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About This Item

UNSPSC Code:
12352202
eCl@ss:
42020141
NACRES:
NA.75
EC Number:
289-149-2
MDL number:
MFCD00131062
Biological source:
bovine plasma
Form:
solution
Technique(s):
cell culture | mammalian: suitable

Key Documents

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Product Name

Fibronectin bovine plasma, solution, sterile-filtered, BioReagent, suitable for cell culture

biological source

bovine plasma

sterility

sterile-filtered

product line

BioReagent

form

solution

packaging

pkg of 1 mg, pkg of 2 mg, pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

surface coverage

1‑5 μg/cm2

UniProt accession no.

P07589

binding specificity

Peptide Source: Collagen
, Peptide Source: Fibrinogen

shipped in

wet ice

storage temp.

2-8°C

Quality Level

200

Gene Information

bovine ... FN1(280794)

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Analysis Note

Protein homogeneity is evaluated by immunoelectrophoresis.

Application

Fibronectin (FN) bovine plasma has been used in:
  • fibronectin and adsorption analysis (ELISA (enzyme-linked immunosorbent assay))
  • transwell migration
  • fibronectin assay

Biochem/physiol Actions

Fibronectins participate in cell adhesion, cytoskeletal organization, oncogenic transformation, cell migration, phagocytosis, hemostasis, and embryonic differentiation.

General description

Fibronectin is a ubiquitous protein of the extracellular matrix. It is a mosaic protein, that is made up of three types of repeating modular consensus amino acid sequences. Fibronectins belongs to a class of high-molecular-weight glycoproteins. Cellular fibronectin is expressed by fibroblasts and plasma fibronectin is usually liberated by hepatocytes.

Other Notes

Product F1141, Fibronectin from bovine plasma is a solution in 0.05 M TBS pH 7.5.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

F1141-PH: + F1141PROC: + F1141-VAR: + F1141-BULK: + F1141-1MG: + F1141-5MG: + F1141-1MG-PW: + F1141-2MG-PW: + F1141-5MG-PW: + F1141-2MG: + F1141-BULK-N:

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Certificates of Analysis (COA)

Lot/Batch Number
0000518561
0000518561
0000463185
0000463185
0000463182

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Role of subnano-, nano-and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells
Khang D, et al.
Biomaterials, 33(26), 5997-6007 (2012)
Tests to predict preeclampsia
Chesley's Hypertensive Disorders in Pregnancy, 221-251 (2015)
CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 and p42/44MAPK dependent mechanisms
Fang W B, et al.
The Journal of biological chemistry, jbc-M112 (2012)
FIBRONECTIN AUTOANTIBODIES
Autoantibodies, 221-251 (2007)
Enhanced fibronectin adsorption on carbon nanotube/poly (carbonate) urethane: independent role of surface nano-roughness and associated surface energy
Khang D, et al.
Biomaterials, 28(32), 4756-4768 (2007)
View All Related Papers

Articles

3D細胞培養のための接着因子

ここでは、細胞外基質（ECM）とその接着因子構成成分の構造生物学的な機能のほか、in vitroでの応用向けにどのようなものが利用できるかについて考察します。

3D細胞培養ツールおよび技術

3D細胞培養の概要2D細胞培養と3D細胞培養の比較、3D細胞培養の利点、3D細胞培養技術について紹介します。

フィブロネクチン

フィブロネクチン（FN）は、細胞外マトリックスの線維の集合と細胞相互作用において極めて重要な役割を果たしています。

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

See All

Protocols

Fibronectin Coating Protocol

Dilute fibronectin for cell attachment, varying per cell type. Coating protocol, products, and FAQs provided.

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