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Merck

G6019

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

Synonym(s):

D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
MDL number:
Specific activity:
50-150 units/mg protein
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form

lyophilized powder

Quality Level

specific activity

50-150 units/mg protein

composition

Protein, 40-70% biuret

UniProt accession no.

foreign activity

3-Phosphoglyceric phosphokinase ≤2%

storage temp.

−20°C

Gene Information

human ... GAPDH(2597)

Biochem/physiol Actions

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Physical form

Lyophilized powder containing sodium citrate buffer salts

Other Notes

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

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