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Merck

H0396

Hydrocortisone-Water Soluble

BioReagent, suitable for cell culture

Synonym(s):

Cyclodextrin-encapsulated hydrocortisone

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About This Item

NACRES:
NA.77
PubChem Substance ID:
24895401
UNSPSC Code:
12352209
MDL number:
MFCD00011654
Biological source:
plant (wild yam)
Form:
crystalline

Key Documents

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Product Name

Hydrocortisone-Water Soluble, BioReagent, suitable for cell culture

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

biological source

plant (wild yam)

product line

BioReagent

form

crystalline

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 400 mg/mL

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)

Related Categories

Application

Hydrocortisone-Water Soluble has been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/high glucose medium to culture mammary alveolar (MAC-T) cells. It has also been used to study its effect on cation absorption by semicircular canal duct epithelium via epithelial sodium channel.

General description

Hydrocortisone has the potential to induce the formation of blood-brain barrier properties in serum-free culture media. It is recommended for use in epithelial and endothelial adherent cell culture applications.

Packaging

Package size based on hydrocortisone

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360Df

Hazard Classifications

Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

H0396-100MG: + H0396-BULK: + H0396-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
0000494105
0000494105
0000493166
0000493166
0000470199

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Brazilian oral research, 34, e033-e033 (2020-04-09)
The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on
Yohan Choi et al.
Asian-Australasian journal of animal sciences, 25(1), 44-51 (2012-01-01)
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