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Merck

H7752

Serotonin creatinine sulfate monohydrate

≥99% (TLC), powder, neurotransmitter

Synonym(s):

3-[2-Aminoethyl]-5-hydroxyindole creatinine sulfate complex, 5-HT, 5-Hydroxytryptamine creatinine sulfate complex

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About This Item

Empirical Formula (Hill Notation):
C14H19N5O2 · H2O4S · H2O
CAS Number:
61-47-2
Molecular Weight:
405.43
UNSPSC Code:
51111800
PubChem Substance ID:
24895804
NACRES:
NA.77
MDL number:
MFCD00149653

Key Documents

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Product Name

Serotonin creatinine sulfate monohydrate, powder

SMILES string

O.OS(O)(=O)=O.CN1CC(=O)NC1=N.NCCc2c[nH]c3ccc(O)cc23

InChI

1S/C10H12N2O.C4H7N3O.H2O4S.H2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;1-7-2-3(8)6-4(7)5;1-5(2,3)4;/h1-2,5-6,12-13H,3-4,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4);1H2

InChI key

BKCXVJIGPVULPX-UHFFFAOYSA-N

form

powder

color

white to off-white

solubility

0.1 M HCl: soluble (Solutions should be freshly prepared.), 95% ethanol: very slightly soluble (Solutions should be freshly prepared.), absolute ethanol: insoluble

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... HTR3A(3359)

Related Categories

Application

Serotonin creatinine sulfate monohydrate has been used:
  • to study its effect on the feeding motions in Caenorhabditis elegans
  • to study the chronotropic responses of serotonin (5-HT) in the zebrafish heart
  • to study the effect of serotonin on isthmus peristalsis

Biochem/physiol Actions

Neurotransmitter.
Serotonin creatinine sulfate stimulates neuronal production of catecholamine.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

H7752-5G: + H7752-1G: + H7752-25G: + H7752-500MG: + H7752-250MG: + H7752-100G: + H7752-BULK: + H7752-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK9522
BCCH8990
BCCF4537
BCCD2035
BCBT6021

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Ryuji Igarashi et al.
Journal of the American Chemical Society, 142(16), 7542-7554 (2020-04-15)
The rotation of an object cannot be fully tracked without understanding a set of three angles, namely, roll, pitch, and yaw. Tracking these angles as a three-degrees-of-freedom (3-DoF) rotation is a fundamental measurement, facilitating, for example, attitude control of a
Effect of serotonin on brown adipose tissue and on its sympathetic neurons
Steiner G and Evans S
The American Journal of Physiology, 231(1), 34-39 (1976)
Methods for measuring pharyngeal behaviors
WormBook: The Online Review of C. elegans Biology (2005)
Adolfo E Talpalar et al.
Nature, 500(7460), 85-88 (2013-07-03)
All forms of locomotion are repetitive motor activities that require coordinated bilateral activation of muscles. The executive elements of locomotor control are networks of spinal neurons that determine gait pattern through the sequential activation of motor-neuron pools on either side
Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans
Song B and Avery L
The Journal of Neuroscience, 32(6), 1920-1931 (2012)
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