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I3265

Interferon-γ human

Name: Interferon-γ human
Brand: SIGMA

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), lyophilized powder, suitable for cell culture

Synonym(s):

IFN-γ

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00131391

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Properties

biological source

human

Quality Level

200

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized powder

mol wt

~17 kDa

packaging

pkg of 0.1 mg

technique(s)

cell culture | mammalian: suitable

impurities

≤1 EU/μg endotoxin

color

white

solubility

water: soluble 1.000 mL, clear, colorless

UniProt accession no.

P01579

storage temp.

−20°C

Gene Information

human ... IFNG(3458)

Description

Application

Interferon-γ human has been used:

to study the effect of interferon-γ on cultured trophoblasts in absence and presence of fibronectin
to analyse factors which participate in the production of antibody microarrays on glass support
for ELISA (enzyme-linked immunosorbent assay) method to understand the effect of interferon-γ in human gingival fibroblasts in presence of bacterial challenge

Biochem/physiol Actions

IFNG (interferon-γ) is a type-2 interferon which is produced by Th (T helper cells)-1 lymphocytes, CD8 cytotoxic lymphocytes, natural killer (NK) cells, and natural killer T (NKT) cells. It plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. High expression of IFNG is common in many autoimmune diseases, such as systemic lupus erythematosis, Sjögren syndrome, inflammatory bowel disease and multiple sclerosis.

Physical form

Lyophilized from phosphate buffered saline.

Analysis Note

The biological activity is measured by a viral resistance assay.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

I3265-.1MG: + I3265-BULK: + I3265-VAR: + I3265-.1MG-PW:

jan

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Certificates of Analysis (COA)

Lot/Batch Number

0000469398

0000227412

079M4071V

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