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Merck

M5162

MOPS

BioXtra, ≥99.5% (titration)

Synonym(s):

3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H15NO4S
CAS Number:
1132-61-2
Molecular Weight:
209.26
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
24896986
EC Number:
214-478-5
Beilstein/REAXYS Number:
1106776
MDL number:
MFCD00006183

Key Documents

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Product Name

MOPS, BioXtra, ≥99.5% (titration)

InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

SMILES string

OS(=O)(=O)CCCN1CCOCC1

grade

reagent grade

sterility

non-sterile

product line

BioXtra

assay

≥99.5% (titration)

form

powder

technique(s)

cell culture | mammalian: suitable
electrophoresis: suitable

impurities

Insoluble matter, passes filter test

ign. residue (900°C)

≤0.1% (as SO4)

loss

≤1% loss on drying, 110°C

pH

2.5-4.0 (1 M in H2O)

useful pH range

6.5-7.9

pKa (25 °C)

7.2

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Na: ≤0.005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.015 at 280 in H2O at 1 M
≤0.020 at 260 in H2O at 1 M

λ

1 M in H2O

suitability

suitable for electrophoresis

Quality Level

400

application(s)

diagnostic assay manufacturing

storage temp.

room temp

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Application


  • Micro-osteoperforations accelerate orthodontic tooth movement by stimulating periodontal ligament cell cycles.: This study explores the use of MOPS buffer in an orthodontic context to promote accelerated tooth movement, enhancing the treatment′s efficiency and patient outcomes (Sugimori et al., 2018).

  • Chitosan-Promoted Direct Electrochemistry of Human Sulfite Oxidase.: Research demonstrates MOPS buffer′s critical role in maintaining enzyme stability and activity during electrochemical studies, providing insights into biochemical applications (Kalimuthu et al., 2017).

  • Peptide fractionation by SDS-free polyacrylamide gel electrophoresis for proteomic analysis via DF-PAGE.: The study uses MOPS buffer in innovative electrophoretic techniques to improve the resolution and separation of peptides, aiding proteomic analyses (Ramos et al., 2012).

Features and Benefits

Features:
  1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
  2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
  3. M-Clarity™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity™ Program
  4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
  5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
  6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
    1. Site quality assessment
    2. ISO 9001 certificate
    3. Detailed product specifications
    4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
Benefits:
  1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
  2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
  3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
  4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
  5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
  6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

General description

MOPS is a morpholino propanesulfonic acid, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.), developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK a with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized.

Other Notes

Easily compare specifications for MOPS products with the MOPS specification table.

Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

M5162-100G: + M5162-BULK: + M5162-25G: + M5162-VAR: + M5162-BULK-PC:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
0000385631
0000385631
0000312109
0000312109
0000478056

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Junji Suzuki et al.
Nature communications, 5, 4153-4153 (2014-06-14)
The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuring
Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability? Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
View All Related Papers

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Product Dossier: Buffers
Product Information Sheet - M5162
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