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Merck

M9500

DL-Methionine

≥99%, suitable for cell culture and insect cell cutlure

Synonym(s):

(±)-2-Amino-4-(methylmercapto)butyric acid, DL-2-Amino-4-(methylthio)butanoic acid

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About This Item

Linear Formula:
CH3SCH2CH2CH(NH2)COOH
CAS Number:
59-51-8
Molecular Weight:
149.21
NACRES:
NA.26
PubChem Substance ID:
24897336
UNSPSC Code:
12352209
EC Number:
200-432-1
MDL number:
MFCD00063096
Beilstein/REAXYS Number:
636185

Key Documents

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Product Name

DL-Methionine, ≥99%

InChI key

FFEARJCKVFRZRR-UHFFFAOYSA-N

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

SMILES string

CSCCC(N)C(O)=O

assay

≥99%

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

color

white

mp

280 °C (dec.) (lit.)

solubility

H2O: soluble

application(s)

peptide synthesis

Quality Level

200

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General description

DL-Methionine is an essential amino acid containing sulphur. Methionine consists of an asymmetric carbon and exists as D (dextrogyre) and L (levogyre) optical isomers. The L-methionine is considered as biologically active. The racemic mixture of D and L-isomers forms DL-methionine, which is the commercially available methionine.

Application

DL-Methionine has been used to study its effect on the growth and feed utilization of Nile tilapia. It has also been used as a part of standard diet in animal models.

Biochem/physiol Actions

DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
Methionine offers protection against disorders related to hair, skin and nails. It elevates lecithin production in the liver and thereby reduces cholesterol level. It naturally serves as a heavy metal chelating agent, regulating ammonia concentration in the urine. This ameliorates bladder irritation. Methionine is also known to induce hair growth.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

M9500-1G: + M9500-500G: + M9500-100G: + M9500-VAR: + M9500-1KG: + M9500-BULK:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6018V
WXBF4998V
WXBF1088V
WXBD7045V
WXBD8984V

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DL-Methionine from Methional and Hydrogen Cyanide - Cost Analysis - Methionine E11A, 6-6 (2016)
Dietary Crystalline DL-Methionine Supplementation of Oilseed Meal-Based Diets: Effects on Growth and Feed Utilization of Juvenile Nile Tilapia (Oreochromis niloticus L.)
Agbo NW, et al.
American Journal of Experimental Agriculture, 4(11), 1385-1396 (2014)
Gel growth and characterization of beta-DL-methionine
Ramachandran E and Natarajan S
Crystal Research and Technology, 41(4), 411-415 (2006)
Glucose homeostasis in mice is transglutaminase 2 independent
Iismaa SE, et al.
PLoS ONE, 8(5), e63346-e63346 (2013)
Partial replacement of fishmeal and fish oil by algal meals in diets of red drum Sciaenops ocellatus
Perez-Velazquez M, et al.
Aquaculture (Amsterdam, Netherlands), 487, 41-50 (2018)
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