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Merck

MAK006

Urea Assay Kit

sufficient for 100 colorimetric tests

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric tests

storage condition

dry at room temperature

technique(s)

activity assay: suitable

input

urine
serum
plasma

detection method

colorimetric

storage temp.

−20°C

General description

The new Urea Assay Kit, MAK471, is now available! Urea is the major end product of nitrogen metabolism in most animals and is produced in a series of reactions in the liver called the urea cycle. In the urea cycle, ammonia is converted to urea, which is carried by blood to the kidneys for elimination from the body. High levels of urea in the blood may indicate renal failure. Urea levels may also be elevated in response to treatment with certain drugs such as corticosteroids or in response to decreased kidney filtration due to dehydration or congestive heart failure. Decreased blood urea levels can occur in response to liver disease or malnutrition.

Application

Suitable for the measurement of urea concentration in a variety of samples such as serum, plasma, and urine, etc.
Urea assay kit has been used to measure the concentration of urea.

Biochem/physiol Actions

In this assay, Urea concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm) product, proportional to the Urea present.

Features and Benefits

Compatible with high-throughput handling systems.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

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pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury.
Ito Y, et al.
Metabolism, Clinical and Experimental, 76, 56-69 (2017)
Nitrogen excretion: three end products, many physiological roles.
Wright P A.
The Journal of Experimental Biology, 198(2), 273-281 (1995)
Inhibition of the RhoGTPase Cdc42 by ML141 enhances hepatocyte differentiation from human adipose-derived mesenchymal stem cells via the Wnt5a/PI3K/miR-122 pathway: impact of the age of the donor.
Chaker D, et al.
Stem Cell Research & Therapy, 9(1), 167-167 (2018)
Hina Hussain et al.
Skin pharmacology and physiology, 32(2), 94-100 (2019-02-21)
Free amino acids (FAAs) and urea, present inside the corneocytes, can be important indicators of skin condition. However, due to the lack of a standard extraction protocol for FAAs from corneocytes, conflicting research results have been reported. Therefore, the purpose
Markers of renal function tests.
Gowda S, et al.
North American Journal of Medical Sciences, 2(4), 170-170 (2010)

Protocols

Assay protocol for the colorimetric detection of Hydroxyproline in biological samples using the Hydroxypoline assay kit.

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