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Merck

T8691

Taurine

suitable for cell culture, BioXtra, meets USP testing specifications

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:
NH2CH2CH2SO3H
CAS Number:
107-35-7
Molecular Weight:
125.15
NACRES:
NA.26
PubChem Substance ID:
24900552
UNSPSC Code:
12352209
EC Number:
203-483-8
MDL number:
MFCD00008197
Beilstein/REAXYS Number:
1751215

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Product Name

Taurine, suitable for cell culture, meets USP testing specifications

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

SMILES string

NCCS(O)(=O)=O

agency

meets USP testing specifications

product line

BioXtra

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

>300 °C (lit.)

Quality Level

200

Gene Information

rat ... Ppm1a(24666)

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Application

Taurine has been used:
  • as a component of cardiomyocyte dissociation solution
  • as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
  • as a constituent of low Ca2+ solution employed in preparation of collagenase B solution for colony dissociation into single cells
  • to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
  • as a component of culture media for derivation of cornea organoids

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

T8691-25KG: + T8691-25G: + T8691-100G: + T8691-VAR: + 2520011: + T8691-1KG: + 2550034: + 2520010: + T8691-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
0000503802
0000503801
0000503801
0000503802
0000464785

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Scalable expansion of human pluripotent stem cells in suspension culture
Zweigerdt R, et al.
Nature Protocols, 6(5), 689-689 (2011)
The Effect of Various Concentrations of Taurine during In vitro Fertilization on the Development of Bovine Embryos Fertilized with Spermatozoa from Three Different Bulls
Tsuzuki Y, et al.
Asian-Australasian Journal of Animal Sciences (2010)
Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells
Zanella F and Sheikh F
Methods in Molecular Biology, 147-162 (2014)
Cornea organoids from human induced pluripotent stem cells
Foster JW, et al.
Scientific Reports, 7 (2017)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
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