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MABF719 Anti-CD62L (L-Selectin) Antibody (mouse), FITC, clone MEL-14

MABF719
500 µg  
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      概要

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M IP, IHC, FC R FITC Monoclonal Antibody
      Description
      Catalogue NumberMABF719
      DescriptionAnti-CD62L (L-Selectin) Antibody (mouse), FITC, clone MEL-14
      Alternate Names
      • L-selectin
      • CD62 antigen-like family member L
      • Leukocyte adhesion molecule 1
      • LAM-1
      • Leukocyte-endothelial cell adhesion molecule 1
      • LECAM1
      • Lymph node homing receptor
      • Lymphocyte antigen 22
      • Ly-22
      • Lymphocyte surface MEL-14 antigen
      • CD62L
      Background InformationThe MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
      References
      Product Information
      FormatFITC
      PresentationPurified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis rat monoclonal antibody Anti-CD62L (L-Selectin) (mouse), FITC, clone MEL-14 validated for use in IP, IHC & Flow Cytometry for the detection of CD62L (L-Selectin).
      Key Applications
      • Immunoprecipitation
      • Immunohistochemistry
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      CloneMEL-14
      Concentration0.5 mg/mL
      HostRat
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Sell
      • Lnhr
      • Ly-22
      • Ly22
      Purification MethodSize Exclusion Chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.25 µg of this antibody detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size500 µg
      Transport Information
      Supplemental Information
      Specifications

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      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies