Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody

Huntingtin-Interacting protein-1 related (HIP1R) is an actin-binding protein that is considered an element of the clathrin-coated pits and vesicles and polymerizes actin. HIP1R is essential for normal actin organization and endocytosis. HIP1R is equipped with a epsin N-terminal homology domain which allows it to bind 3-phosphorylated inositol lipids, which allows HIP1R to function as a tyrosine kinase stabilizing receptor and plays a role in overall cell growth and survival.

~116 kDa

Synthetic peptide

Detect Huntingtin-Interacting Protein 1 Related (HIP1R) using this Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody validated for use in WB & IC.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Synapse & Synaptic Biology

Western Blot: a 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.A 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.

Immunocytochemistry: a previous lot of this antibody was used by an independent laboratory for IC of human cells. (Poupon, V., et al. (2008). PNAS. 105(1): 168-173.)

Optimal working dilutions must be determined by end user.

Huntingtin-interacting protein 1 related (HIP1R). By Western blot the antibody recognizes a band at ~116 kDa on P2 microsomal fraction from embryonic rat brain.

Format: Purified

Liquid

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

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