数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

AM76 Sigma-AldrichAnti-TBK1 Mouse mAb (108A429)

This Anti-TBK1 Mouse mAb (108A429) is validated for use in Immunoblotting for the detection of TBK1.

Anti-TBK1 Mouse mAb (108A429): のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

お勧めの製品

概要

Replacement Information

主要スペック表

Species Reactivity	Host	Antibody Type
H	M	Monoclonal Antibody

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
AM76-100UGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	100 μg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	Recognizes the ~80 kDa TBK1 protein in HEK293 cells.
Catalogue Number	AM76
Brand Family	Calbiochem®
Application Data	Detection of human TBK1 by immunoblotting. Samples: Whole cell lysates from 293 cells untransfected (lane 1) and transfected with human TBK1 cDNA (lane 2). Primary antibody: Anti-TBK1 Mouse mAb (108A429) (Cat. No. AM76) (2 µg/ml). Detection: chemiluminescence. Detection of TBK1 by immunoblotting. Samples: Whole cell lysates from human Daudi cells (lane 1) and mouse RAW cells (lane 2). Primary antibody: Anti-TBK1 Mouse mAb (108A429) (Cat. No. AM76) (2 µg/ml). Detection: chemiluminescence.

References
References	Pomeerantz, J.L. and Baltimore, D. 1999. EMBO J. 18, 6694. Didonato, J.A., et al. 1997. Nature 388, 548. Lee, F.S., et al. 1997. Cell 88, 213. Malinin, N.L., et al. 1997. Nature 385, 540. Mercurio, F., et al. 1997. Science 278, 860. Regnier, C.H., et al. 1997. Cell 90, 373. Verma, I. and Stevenson, J.K. 1997. Proc. Natl. Acad. Sci. USA 94, 11758. Verma, I.M., et al. 1995. Genes Dev. 9, 2723.

References

Pomeerantz, J.L. and Baltimore, D. 1999. EMBO J. 18, 6694.
Didonato, J.A., et al. 1997. Nature 388, 548.
Lee, F.S., et al. 1997. Cell 88, 213.
Malinin, N.L., et al. 1997. Nature 385, 540.
Mercurio, F., et al. 1997. Science 278, 860.
Regnier, C.H., et al. 1997. Cell 90, 373.
Verma, I. and Stevenson, J.K. 1997. Proc. Natl. Acad. Sci. USA 94, 11758.
Verma, I.M., et al. 1995. Genes Dev. 9, 2723.

Product Information
Form	Liquid
Formulation	In PBS, 0.2% gelatin.
Negative control	Normal mouse serum
Positive control	HEK293 cells
Preservative	≤0.1% sodium azide
Quality Level	MQ100

Applications
Key Applications	Immunoblotting (Western Blotting)
Application Notes	Immunoblotting (2 µg/ml)
Application Comments	Antibody should be titrated for optimal results in an individual systems.

Biological Information
Immunogen	full-length, recombinant, human TBK1 fused to a His•Tag^® sequence
Immunogen	Human
Clone	108A429
Host	Mouse
Isotype	IgG₁
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Blue Ice Only
Toxicity	Standard Handling
Storage	-20°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
AM76-100UGCN	04055977228045

Documentation

Anti-TBK1 Mouse mAb (108A429) (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

Anti-TBK1 Mouse mAb (108A429) 試験成績書（CoA）

タイトル	ロット番号
AM76	ロット番号を入力

参考資料

参考資料の概要
Pomeerantz, J.L. and Baltimore, D. 1999. EMBO J. 18, 6694. Didonato, J.A., et al. 1997. Nature 388, 548. Lee, F.S., et al. 1997. Cell 88, 213. Malinin, N.L., et al. 1997. Nature 385, 540. Mercurio, F., et al. 1997. Science 278, 860. Regnier, C.H., et al. 1997. Cell 90, 373. Verma, I. and Stevenson, J.K. 1997. Proc. Natl. Acad. Sci. USA 94, 11758. Verma, I.M., et al. 1995. Genes Dev. 9, 2723.

参考資料の概要

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-August-2007 RFH
Application	Immunoblotting (2 µg/ml)
Application Data	Detection of human TBK1 by immunoblotting. Samples: Whole cell lysates from 293 cells untransfected (lane 1) and transfected with human TBK1 cDNA (lane 2). Primary antibody: Anti-TBK1 Mouse mAb (108A429) (Cat. No. AM76) (2 µg/ml). Detection: chemiluminescence. Detection of TBK1 by immunoblotting. Samples: Whole cell lysates from human Daudi cells (lane 1) and mouse RAW cells (lane 2). Primary antibody: Anti-TBK1 Mouse mAb (108A429) (Cat. No. AM76) (2 µg/ml). Detection: chemiluminescence.
Description	Protein G purified mouse monoclonal antibody. Recognizes the ~80 kDa TBK1 protein.
Background	Nuclear factor κB (NF-κB) is sequestered in cell cytoplasm by the IκB family of inhibitory proteins that mask the nuclear localization signal of NF-κB, preventing its translocation to the nucleus. Stimulus by tumor necrosis factor or other cytokines results in the phosphorylation and degradation of IκB, releasing NF-κB dimers. These dimers then translocate to the nucleus and activate target genes. IκBα synthesis is autoregulated. IκB proteins are phosphorylated by an IκB kinase made up of at least three proteins; IKK1/α, IKK2/β, and IKK3/γ. IKK 1/α and IKK2/β are phosphorylated by NF-κB-inducing kinase (NIK) and MAP kinase kinase kinase-1 (MEKK1) respectively. TANK-binding kinase (TBK1) has recently been identified as a member of the IKK family. TRAF-associated NF-κB activator (TANK) interacts with TBK1 and activates NF-κB in a kinase-dependent manner.
Host	Mouse
Immunogen species	Human
Immunogen	full-length, recombinant, human TBK1 fused to a His•Tag^® sequence
Clone	108A429
Isotype	IgG₁
Species	human
Positive control	HEK293 cells
Negative control	Normal mouse serum
Form	Liquid
Formulation	In PBS, 0.2% gelatin.
Concentration Label	Please refer to vial label for lot-specific concentration
Preservative	≤0.1% sodium azide
Comments	Antibody should be titrated for optimal results in an individual systems.
Storage	Avoid freeze/thaw -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Standard Handling
References	Pomeerantz, J.L. and Baltimore, D. 1999. EMBO J. 18, 6694. Didonato, J.A., et al. 1997. Nature 388, 548. Lee, F.S., et al. 1997. Cell 88, 213. Malinin, N.L., et al. 1997. Nature 385, 540. Mercurio, F., et al. 1997. Science 278, 860. Regnier, C.H., et al. 1997. Cell 90, 373. Verma, I. and Stevenson, J.K. 1997. Proc. Natl. Acad. Sci. USA 94, 11758. Verma, I.M., et al. 1995. Genes Dev. 9, 2723.

カテゴリー

Life Science Research > Antibodies and Assays > Primary Antibodies

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