Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, Cy5 conjugate

This antibody recognizes a variety of proteins that are phosphorylated during mitosis.

Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M-phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M-phase enzymatic activities and structures. Also, known as Forkhead-related protein FKHL16 or Hepatocyte nuclear factor 3 forkhead homolog 11.

Mitotic human HeLa cell lysate

Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, Cy5 conjugate is a Mouse Monoclonal Antibody for detection of phospho-Ser/Thr-Pro also known as Mitotic protein #2 & has been tested in IF, WB, ICC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Recognizes a phosphorylated epitope (phospho-[Ser/Thr]Pro) found in phosphoproteins such as MAP2, HSP70, cdc25, and DNA topoisomerase IIα, most of which are phosphorylated at the onset of mitosis. The number of phosphoproteins recognized by MPM-2 varies from species to species and with the cell type.

100μg Cy5-conjugated mouse IgG₁ in 200μl of PBS containing 1% BSA, 0.05% Tween^®-20, 0.05% sodium azide.

Protein G Purified

1 year at 4°C from date of shipment

Control
Colcemid-treated HeLa cell lysates

Routinely evaluated by immunoblot on colcemid-treated HeLa cell lysates.

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