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233553 COCO, Human, Recombinant

COCO, Human, Recombinant consists of amino acids 23-189 and is expressed in E. coli with an N-terminal methionine. Inhibits BMP-4 induced activity in MC3T3-E1 cells. ED₅₀ = 0.15-0.75 µg/ml.

COCO, Human, Recombinant: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: DAND5 Dante CKTSF1B3

233553
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概要

Replacement Information

主要スペック表

Purity
≥95% by SDS-PAGE

価格＆在庫状況

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233553-50UGCN
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      		 ｶﾞﾗｽﾋﾞﾝ 50 μg
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      Description
      OverviewRecombinant, human COCO consisting of amino acids 23-189 and expressed in E. coli with an N-terminal methionine. Inhibits BMP-4 induced activity in MC3T3-E1 mouse osteoblastic cells. ED 50 = 0.15-0.75 µg/ml. Human COCO, at the amino acid sequence level, is 60% and 24% identical with mouse and Xenopus COCO, respectively.
      Catalogue Number233553
      Brand Family Calbiochem®
      SynonymsDAND5 Dante CKTSF1B3
      References
      ReferencesBaron, M.H., 2005. Exp. Hematol. 33, 1015. Katoh, M. and M. Katoh. 2005. Int. J. Mol. Med. 15, 885. Kishigami, S. and Y. Mishina. 2005. Cytokine Growth FactorRev. 16, 265. AvsianKretchmer, O. and A.J.W. Hsueh. 2004. Mol. Endocrinol. 18, 1. De Robertis, E.M. and H. Koruda. 2004. Annu. Rev. Cell Dev. Biol. 20, 285. Katoh, M. and M. Katoh. 2004. Oncol. Rep. 12, 423. Bell, E., et al. 2003. Development 130, 1381. Pearce, J.J. et al., 1999. Dev. Biol. 209, 98.
      Product Information
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA, BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.15 0.75 µg/ml in the presence of 50 ng/ml of rhBMP-4 as measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse osteoblastic cells.
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      233553-50UGCN 04055977217902

      Documentation

      COCO, Human, Recombinant 試験成績書（CoA）

      タイトルロット番号
      233553

      参考資料

      参考資料の概要
      Baron, M.H., 2005. Exp. Hematol. 33, 1015. Katoh, M. and M. Katoh. 2005. Int. J. Mol. Med. 15, 885. Kishigami, S. and Y. Mishina. 2005. Cytokine Growth FactorRev. 16, 265. AvsianKretchmer, O. and A.J.W. Hsueh. 2004. Mol. Endocrinol. 18, 1. De Robertis, E.M. and H. Koruda. 2004. Annu. Rev. Cell Dev. Biol. 20, 285. Katoh, M. and M. Katoh. 2004. Oncol. Rep. 12, 423. Bell, E., et al. 2003. Development 130, 1381. Pearce, J.J. et al., 1999. Dev. Biol. 209, 98.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-Sepmtember-2011 RFH
      SynonymsDAND5 Dante CKTSF1B3
      DescriptionRecombinant, human COCO consisting of amino acids 23-189 and expressed in E. coli with an N-terminal methionine. Inhibits BMP-4 induced activity in MC3T3-E1 mouse osteoblastic cells. ED 50 = 0.15-0.75 µg/ml. Human COCO, at the amino acid sequence level, is 60% and 24% identical with mouse and Xenopus COCO, respectively.
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA, BSA.
      Purity≥95% by SDS-PAGE
      Biological activityED₅₀ = 0.15 0.75 µg/ml in the presence of 50 ng/ml of rhBMP-4 as measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse osteoblastic cells.
      SolubilityReconstitute to 200 µg/ml in sterile 4 mM HCI containing at least 0.1% human or bovine serum albumin.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBaron, M.H., 2005. Exp. Hematol. 33, 1015. Katoh, M. and M. Katoh. 2005. Int. J. Mol. Med. 15, 885. Kishigami, S. and Y. Mishina. 2005. Cytokine Growth FactorRev. 16, 265. AvsianKretchmer, O. and A.J.W. Hsueh. 2004. Mol. Endocrinol. 18, 1. De Robertis, E.M. and H. Koruda. 2004. Annu. Rev. Cell Dev. Biol. 20, 285. Katoh, M. and M. Katoh. 2004. Oncol. Rep. 12, 423. Bell, E., et al. 2003. Development 130, 1381. Pearce, J.J. et al., 1999. Dev. Biol. 209, 98.