Millipore Sigma Vibrant Logo

05-23-3800 Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

Endothelin 1, Human and Porcine, CAS 117399-94-7, is a 21-amino acid polypeptide with potent vasoconstrictive action. Activates phospholipase C in fibroblasts expressing ETA receptors.

Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: ET-1, CSCSSLMDKECVYFCHLDIIW

Primary Target: Potent vasoconstrictive action
View This Product on Sigma-Aldrich
05-23-3800
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

CAS #Empirical Formula
117399-94-7C₁₀₉H₁₅₉N₂₅O₃₂S₅

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
05-23-3800-0.1MGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ .1 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      05-23-3800-0.5MGCN
      在庫状況検索中…
      —
      現在国内在庫なし 現在国内在庫なし
      現在国内在庫有り 
      販売中止
      在庫僅少
      現在国内在庫あり
        Remaining : Will advise
          Remaining : Will advise
          注文対象外
          お問合せください
          Contact Customer Service

          		 樹脂ｱﾝﾌﾟﾙ .5 mg
          価格を検索中…
          価格が見つかりません
          Minimum Quantity needs to be mulitiple of
          Maximum Quantity is
          弊社照会 詳細を表示　
          値引
          ()
           
          —
          弊社照会
          		 —
          05-23-3800-1MGCN
          在庫状況検索中…
          —
          現在国内在庫なし 現在国内在庫なし
          現在国内在庫有り 
          販売中止
          在庫僅少
          現在国内在庫あり
            Remaining : Will advise
              Remaining : Will advise
              注文対象外
              お問合せください
              Contact Customer Service

              		 樹脂ｱﾝﾌﾟﾙ 1 mg
              価格を検索中…
              価格が見つかりません
              Minimum Quantity needs to be mulitiple of
              Maximum Quantity is
              弊社照会 詳細を表示　
              値引
              ()
               
              —
              弊社照会
              		 —
              Description
              OverviewA 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
              Catalogue Number05-23-3800
              Brand Family Calbiochem®
              SynonymsET-1, CSCSSLMDKECVYFCHLDIIW
              References
              ReferencesCesari, M., et al. 1996. Am. Heart J. 132, 1236.
              Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
              Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
              Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
              Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
              Yanagisawa, M., et al. 1988. Nature 332, 411.
              Product Information
              CAS number117399-94-7
              ATP CompetitiveN
              FormWhite to off-white solid
              FormulationSupplied as an acetate salt.
              Hill FormulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
              Chemical formulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
              ReversibleN
              Sold on the basis of peptide contentY
              Quality LevelMQ100
              Applications
              Biological Information
              Primary TargetPotent vasoconstrictive action
              Purity≥96% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceH-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Protect from Moisture Protect from moisture
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              カタログ番号 GTIN
              05-23-3800-0.1MGCN 04055977226775
              05-23-3800-0.5MGCN 04055977226782
              05-23-3800-1MGCN 04055977226799

              Documentation

              Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem (M)SDS

              タイトル

              英語版製品安全データシート（(M)SDS） 

              Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem 試験成績書（CoA）

              タイトルロット番号
              05-23-3800

              参考資料

              参考資料の概要
              Cesari, M., et al. 1996. Am. Heart J. 132, 1236.
              Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
              Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
              Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
              Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
              Yanagisawa, M., et al. 1988. Nature 332, 411.
              データシート

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision12-May-2008 JSW
              SynonymsET-1, CSCSSLMDKECVYFCHLDIIW
              DescriptionA 21 amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
              FormWhite to off-white solid
              FormulationSupplied as an acetate salt.
              CAS number117399-94-7
              Chemical formulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
              Peptide SequenceH-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
              Purity≥96% by HPLC
              Solubility5% Acetic acid (0.5 mg/ml). Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with distilled water to achieve 5% acetic acid and 0.5 mg/ml peptide.
              Storage Protect from moisture
              -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
              Toxicity Standard Handling
              ReferencesCesari, M., et al. 1996. Am. Heart J. 132, 1236.
              Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
              Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
              Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
              Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
              Yanagisawa, M., et al. 1988. Nature 332, 411.