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Merck

FCMAB103AP

Milli-Mark Anti-Ki67 Antibody, clone Ki-S5 APC conjugate

clone Ki-S5, Milli-Mark®, from mouse

別名:

MKI67

KIA

Ki-67

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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製品名

Milli-Mark Anti-Ki67 Antibody, clone Ki-S5 APC conjugate, clone Ki-S5, Milli-Mark®, from mouse

biological source

mouse

conjugate

Allophycocyanin conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

Ki-S5, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... MKI67(4288)

関連するカテゴリー

Application

Detect Ki67 using this Milli-Mark Anti-Ki67 Antibody, clone Ki-S5 APC conjugate validated for use in FC, IC, IH, FC, IH(P).
Research Category
Signaling
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

Antibody recognizes Ki67.

Analysis Note

Control
Stimulated Jurkat Cells
Evaluated by Flow Cytometry with Jurkat cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

345 & 395 kDa observed
Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a marker of cell cycling and proliferation. This specificity of Ki-S5 antibody for proliferating cells might make it a useful tool for determination of the proliferative fraction in tumors such as Non-Hodgkin′s lymphoma (Kreipe et al., 1993), mammary carcinomas (Mauri et al., 1984), ovarian tumors (Ballin et al., 1994) and prostate cancer.

Immunogen

Nuclear protein preparation from the human cell line U937.50

Physical form

Protein A purified
Purified mouse monoclonal IgG1 conjugated to Allophycocyanin (APC) in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


試験成績書(COA)

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文書ライブラリにアクセスする

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グローバルトレードアイテム番号

カタログ番号GTIN
FCMAB103AP04053252471735

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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