Millipore Sigma Vibrant Logo

567021 Simvastatin, Sodium Salt - Calbiochem

Simvastatin, Sodium Salt is a carboxylate form of Simvastatin. Active in whole cells and in cell-free preparations. An inhibitor of HMG-CoA reductase.

Simvastatin, Sodium Salt - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: L-Type Calcium Channel Blocker VI

Primary Target: 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
567021
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

Empirical Formula
C₂₅H₃₉O₆ • Na

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
567021-50MGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 ｶﾞﾗｽﾋﾞﾝ 50 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      567021-5MGCN
      在庫状況検索中…
      —
      現在国内在庫なし 現在国内在庫なし
      現在国内在庫有り 
      販売中止
      在庫僅少
      現在国内在庫あり
        Remaining : Will advise
          Remaining : Will advise
          注文対象外
          お問合せください
          Contact Customer Service

          		 樹脂ｱﾝﾌﾟﾙ 5 mg
          価格を検索中…
          価格が見つかりません
          Minimum Quantity needs to be mulitiple of
          Maximum Quantity is
          弊社照会 詳細を表示　
          値引
          ()
           
          —
          弊社照会
          		 —
          Description
          OverviewCarboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free preparations. Also available as a 10 mM solution in H2O (Cat. No. 567022).
          Catalogue Number567021
          Brand Family Calbiochem®
          SynonymsL-Type Calcium Channel Blocker VI
          References
          ReferencesYada, T., et al. 1999. Br. J. Pharmacol. 126, 1205.
          Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522.
          Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87.
          Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259.
          Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016.
          Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.
          Product Information
          ATP CompetitiveN
          FormBeige solid
          Hill FormulaC₂₅H₃₉O₆ • Na
          Chemical formulaC₂₅H₃₉O₆ • Na
          HS Code2932 20 00
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Target3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          カタログ番号 GTIN
          567021-50MGCN 04055977267112
          567021-5MGCN 07790788051587

          Documentation

          Simvastatin, Sodium Salt - Calbiochem 試験成績書（CoA）

          タイトルロット番号
          567021

          参考資料

          参考資料の概要
          Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205.
          Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522.
          Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87.
          Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259.
          Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016.
          Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.
          データシート

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-October-2015 JSW
          SynonymsL-Type Calcium Channel Blocker VI
          DescriptionCarboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+-signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. Note: This product is supplied in an active form; no treatment with NaOH in ethanol is required for its activation.
          FormBeige solid
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₂₅H₃₉O₆ • Na
          Structure formulaStructure formula
          Purity≥97% by HPLC
          SolubilityDMSO (100 mg/ml), Ethanol (25 mg/ml), or H₂O (5 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesYada, T., et al. 1999. Br. J. Pharmacol. 126, 1205.
          Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522.
          Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87.
          Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259.
          Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016.
          Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.