05-23-0600 Substance P - CAS 33507-63-0 - Calbiochem

05-23-0600
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概要

Replacement Information

主要スペック表

Empirical FormulaCAS #
C₆₃H₉₈N₁₈O₁₃S 33507-63-0

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
05-23-0600-1MGCN
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      樹脂アンプル 1 mg
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      05-23-0600-25MGCN
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          樹脂アンプル 25 mg
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          05-23-0600-5MGCN
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              樹脂アンプル 5 mg
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              Description
              OverviewNeuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goα, Gq/11α, and Gsα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
              Catalogue Number05-23-0600
              Brand Family Calbiochem®
              SynonymsRPKPQQFFGLM
              References
              ReferencesRoush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
              Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
              Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
              Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
              Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
              Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
              Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.
              Product Information
              CAS number33507-63-0
              ATP CompetitiveN
              FormWhite solid
              FormulationSupplied as a trifluoroacetate salt.
              Hill FormulaC₆₃H₉₈N₁₈O₁₃S
              Chemical formulaC₆₃H₉₈N₁₈O₁₃S
              Hygroscopic Hygroscopic
              ReversibleN
              Sold on the basis of peptide contentY
              Quality LevelMQ100
              Applications
              Biological Information
              Primary TargetSubstance P receptors
              Purity≥96% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Substance P - CAS 33507-63-0 - Calbiochem (M)SDS

              タイトル

              英語版製品安全データシート((M)SDS) 

              Substance P - CAS 33507-63-0 - Calbiochem 試験成績書(CoA)

              タイトルロット番号
              05-23-0600

              参考資料

              参考資料の概要
              Roush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
              Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
              Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
              Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
              Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
              Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
              Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.
              データシート

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision23-June-2008 RFH
              SynonymsRPKPQQFFGLM
              DescriptionNeuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goα, Gq/11α, and Gsα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
              FormWhite solid
              FormulationSupplied as a trifluoroacetate salt.
              CAS number33507-63-0
              Chemical formulaC₆₃H₉₈N₁₈O₁₃S
              Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂
              Purity≥96% by HPLC
              Solubility5% Acetic Acid (1 mg/ml)
              Storage -20°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
              Toxicity Standard Handling
              Merck USA index14, 8863
              ReferencesRoush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
              Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
              Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
              Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
              Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
              Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
              Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.