Anti-Survivin Antibody

Apoptosis is triggered by a variety of stimuli, including members of the Tumor Necrosis Factor (TNF) family, and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. One of these IAP proteins, Survivin/TIAP, interacts with the processed form of caspase-3 and has been shown to inhibit its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.

Peptide corresponding to aa 128-140 of mouse survivin/TIAP.

Anti-Survivin Antibody is an antibody against Survivin for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
BCL2 & Inhibition

Western blot: 1:500 to 1:1000

Mouse spleen tissue lysate can be used as a positive control.

Optimal working dilutions must be determined by end user.

Detects mouse survivin/TIAP in an approximate 17 kDa band by western blot.

Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Maintain at 4°C for up to 6 months.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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